2022
Effect of chemotherapy on the uterus of young adult cancer survivors
Garg D, Hodgman M, Reil S, Lomo L, Aston K, Hill J, Johnstone E, Jenkins T, Letourneau J. Effect of chemotherapy on the uterus of young adult cancer survivors. F&S Reports 2022, 3: 198-203. PMID: 36212573, PMCID: PMC9532891, DOI: 10.1016/j.xfre.2022.05.008.Peer-Reviewed Original ResearchEndometrial thicknessChemotherapy exposureEndometrial biopsyUterine volumeCancer survivorsHodgkin's lymphomaMenstrual cycleDeoxyribonucleic acid (DNA) methylation patternsCross-sectional pilot studyYoung adult cancer survivorsImpact of chemotherapyRibonucleic acid expression levelsEffect of chemotherapyAdult cancer survivorsGeneral population controlsLate proliferative phaseMedian uterine volumeUniversity fertility clinicPelvic radiationEndometrial histologyPelvic ultrasoundCervical cancerFalse-positive resultsMenstruating womenStudy visit
2020
Looking beyond the ovary for oncofertility care in women: uterine injury as a potential target for fertility-preserving treatments
Garg D, Johnstone E, Lomo L, Fair D, Rosen M, Taylor R, Silver B, Letourneau J. Looking beyond the ovary for oncofertility care in women: uterine injury as a potential target for fertility-preserving treatments. Journal Of Assisted Reproduction And Genetics 2020, 37: 1467-1476. PMID: 32342270, PMCID: PMC7311602, DOI: 10.1007/s10815-020-01792-9.Peer-Reviewed Original ResearchConceptsCancer survivorsPregnancy complicationsObstetrical outcomesFertility-preserving treatmentLow birth weightPoor obstetrical outcomesFemale cancer survivorsImpact of chemotherapyEarly pregnancy lossOncofertility carePregnancy implantationLate complicationsPregnancy outcomesPreterm birthRadiation fibrosisEndometrial receptivityGonadotoxic effectsUterine injuryBirth weightPregnancy lossPregnant uterusBlood supplyUterine functionChemotherapyComplications