1989
Effect of varying drop size on the efficacy and safety of a topical beta blocker.
Charap A, Shin D, Petursson G, Cinotti D, Wortham E, Brown R, Silverstone D, Atkins J, Eto C, Lue J. Effect of varying drop size on the efficacy and safety of a topical beta blocker. Annals Of Ophthalmology - Glaucoma 1989, 21: 351-7. PMID: 2683937.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, TopicalAdultBlood PressureDosage FormsDose-Response Relationship, DrugDouble-Blind MethodElectrocardiographyExercise TestFollow-Up StudiesGlaucoma, Open-AngleHeart RateHumansIntraocular PressureLevobunololMiddle AgedMulticenter Studies as TopicRandom AllocationTime FactorsVisual AcuityConceptsIntraocular pressureBeta blockersHeart rateMicroL of vehicleTopical beta blockersMean intraocular pressureElevated intraocular pressureMean heart rateLevobunolol 0.5Levobunolol groupBlood pressureAcute studyTopical solutionVehicle groupChronic studiesMean decreaseControl groupOne hourEfficacyLevobunololBlockersSafetyGroupMicroLPatients
1985
Levobunolol vs Timolol for Open-Angle Glaucoma and Ocular Hypertension
Galin M, Cinotti A, Cinotti D, Grant W, Jacobs I, Silverstone D, Shin D, Esters J, Lee J, Bouchey R, Novack G, Duzman E, Lue J. Levobunolol vs Timolol for Open-Angle Glaucoma and Ocular Hypertension. American Journal Of Ophthalmology 1985, 99: 11-17. PMID: 3881032, DOI: 10.1016/s0002-9394(14)75859-3.Peer-Reviewed Original ResearchConceptsOpen-angle glaucomaIntraocular pressureOcular hypertensionMean reductionChronic open-angle glaucomaPercent of patientsTopical ophthalmic solutionOverall mean reductionLife-table estimatesSuccessful treatmentLevobunololOphthalmic solutionPatientsTimololHypertensionSignificant differencesGlaucomaHgMonths