Association of Biologically Effective Dose and Survival in Patients Receiving Head and Neck Stereotactic Body Radiation Therapy
Márquez C, Phan J, Lee A, Reddy J, Garden A, Gunn G, Frank S, Fuller C, Moreno A, Morrison W, Rosenthal D, Spiotto M. Association of Biologically Effective Dose and Survival in Patients Receiving Head and Neck Stereotactic Body Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: e770-e771. DOI: 10.1016/j.ijrobp.2024.07.1694.Peer-Reviewed Original ResearchStereotactic body radiation therapyHead and neck cancerBiologically effective doseRadiation therapyPerformance statusN stagePatients treated with stereotactic body radiation therapyTreat recurrent head and neck cancerPatients treated with initial surgeryRecurrent head and neck cancerHigher biologically effective dosesIncreasing BEDMedian follow-up durationAssociated with improved survivalHead and neck cancer patientsEffective doseNo survival improvementSurgically resected patientsNational Cancer DatabaseFractionation schemeAssociated with enhanced survivalCox regression modelsDose escalationHPV statusResected patientsMR-guided stereotactic radiation therapy for head and neck cancers
Wang H, Yang J, Lee A, Phan J, Lim T, Fuller C, Han E, Rhee D, Salzillo T, Zhao Y, Chopra N, Pham M, Castillo P, Sobremonte A, Moreno A, Reddy J, Rosenthal D, Garden A, Wang X. MR-guided stereotactic radiation therapy for head and neck cancers. Clinical And Translational Radiation Oncology 2024, 46: 100760. PMID: 38510980, PMCID: PMC10950743, DOI: 10.1016/j.ctro.2024.100760.Peer-Reviewed Original ResearchAdapt-to-shapeStereotactic body radiation therapyIMRT plansVMAT plansTarget coverageMR-LinacPlan qualityAdapt-to-shape workflowElekta Unity MR-linacMonaco treatment planning systemSoft tissue contrastVMAT treatment plansTreatment planning systemUnity MR-linacCritical organ dosesMR-guided radiotherapyHead and neckAdapt-to-positionRadiation therapyMean doseVarian TrueBeamTrueBeam STxOAR dosesDosimetric differencesElekta Unity