Publications

Showing 1 - 20 of 31 Publications

2025

Low Stability and Specificity of Polygenic Risk Scores for Major Psychiatric Disorders Limit their Clinical Utility
Mollon J, Schultz L, Knowles E, Jacquemont S, Glahn D, Almasy L. Low Stability and Specificity of Polygenic Risk Scores for Major Psychiatric Disorders Limit their Clinical Utility. Biological Psychiatry 2025 PMID: 40113122, DOI: 10.1016/j.biopsych.2025.03.006.
Peer-Reviewed Original Research
Concepts
Genetic Associations Among Inflammation, White Matter Architecture, and Extracellular Free Water
Rodrigue A, Knowles E, Mollon J, Mathias S, Peralta J, Leandro A, Fox P, Kochunov P, Olvera R, Almasy L, Curran J, Blangero J, Glahn D. Genetic Associations Among Inflammation, White Matter Architecture, and Extracellular Free Water. Human Brain Mapping 2025, 46: e70101. PMID: 39757975, PMCID: PMC11702472, DOI: 10.1002/hbm.70101.
Peer-Reviewed Original Research
MeSH Keywords and Concepts

2024

Effects of gene dosage on cognitive ability: A function-based association study across brain and non-brain processes
Huguet G, Renne T, Poulain C, Dubuc A, Kumar K, Kazem S, Engchuan W, Shanta O, Douard E, Proulx C, Jean-Louis M, Saci Z, Mollon J, Schultz L, Knowles E, Cox S, Porteous D, Davies G, Redmond P, Harris S, Schumann G, Dumas G, Labbe A, Pausova Z, Paus T, Scherer S, Sebat J, Almasy L, Glahn D, Jacquemont S. Effects of gene dosage on cognitive ability: A function-based association study across brain and non-brain processes. Cell Genomics 2024, 4: 100721. PMID: 39667348, PMCID: PMC11701252, DOI: 10.1016/j.xgen.2024.100721.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Impact of Type 2 Diabetes and Hypertension on Cognition: A Propensity Score‐Matched Analysis in Mexican Americans from San Antonio
Lopez‐Alvarenga J, Almeida M, Cavazos J, Mahaney M, Maestre G, Glahn D, Duggirala R, Blangero J. Impact of Type 2 Diabetes and Hypertension on Cognition: A Propensity Score‐Matched Analysis in Mexican Americans from San Antonio. Alzheimer's & Dementia 2024, 20: e091135. PMCID: PMC11716190, DOI: 10.1002/alz.091135.
Peer-Reviewed Original Research
Concepts
Virtual stressors with real impact: what virtual reality-based biobehavioral research can teach us about typical and atypical stress responsivity
Shirtcliff E, Finseth T, Winer E, Glahn D, Conrady R, Drury S. Virtual stressors with real impact: what virtual reality-based biobehavioral research can teach us about typical and atypical stress responsivity. Translational Psychiatry 2024, 14: 441. PMID: 39420000, PMCID: PMC11487258, DOI: 10.1038/s41398-024-03129-x.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Comparative Analysis of Fecal Microbiota Between Adolescents with Early-Onset Psychosis and Adults with Schizophrenia
Nuncio-Mora L, Nicolini H, Lanzagorta N, García-Jaimes C, Sosa-Hernández F, González-Covarrubias V, Cabello-Rangel H, Sarmiento E, Glahn D, Genis-Mendoza A. Comparative Analysis of Fecal Microbiota Between Adolescents with Early-Onset Psychosis and Adults with Schizophrenia. Microorganisms 2024, 12: 2071. PMID: 39458380, PMCID: PMC11510430, DOI: 10.3390/microorganisms12102071.
Peer-Reviewed Original Research
Concepts
RESOLVING THE CHALLENGES OF BIG-DATA IMAGING GENETICS ANALYSIS TO UNDERSTAND GENETIC AND ENVIRONMENTAL RISK FACTORS IN PSYCHIATRIC DISORDERS
Kochunov P, Nichols T, Blangero J, Medland S, Glahn D, Hong E. RESOLVING THE CHALLENGES OF BIG-DATA IMAGING GENETICS ANALYSIS TO UNDERSTAND GENETIC AND ENVIRONMENTAL RISK FACTORS IN PSYCHIATRIC DISORDERS. European Neuropsychopharmacology 2024, 87: 21-22. DOI: 10.1016/j.euroneuro.2024.08.056.
Peer-Reviewed Original Research
Concepts
94. THE GENETIC ARCHITECTURE OF MOOD AND ANXIETY DISORDER SYMPTOMS
Schultz L, Mollon J, Jacquemont S, Almasy L, Glahn D. 94. THE GENETIC ARCHITECTURE OF MOOD AND ANXIETY DISORDER SYMPTOMS. European Neuropsychopharmacology 2024, 87: 100. DOI: 10.1016/j.euroneuro.2024.08.208.
Peer-Reviewed Original Research
Concepts
6.25 Characterization of Abnormal Pain and Somatization in Early-Onset Psychosis
van der Heijden H, Goldman M, Ray A, Golden M, Petty C, Deaso E, Hojlo M, Sethna N, Glahn D, Gonzalez-Heydrich J. 6.25 Characterization of Abnormal Pain and Somatization in Early-Onset Psychosis. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024, 63: s289. DOI: 10.1016/j.jaac.2024.08.423.
Peer-Reviewed Original Research
Characterization of pain and somatization and its relationship with psychopathology in early onset psychosis
van der Heijden H, Goldman M, Ray A, Golden E, Petty C, Deaso E, Hojlo M, Sethna N, Glahn D, Gonzalez-Heydrich J, Upadhyay J. Characterization of pain and somatization and its relationship with psychopathology in early onset psychosis. Journal Of Psychiatric Research 2024, 179: 77-82. PMID: 39260111, PMCID: PMC11531992, DOI: 10.1016/j.jpsychires.2024.09.006.
Peer-Reviewed Original Research
Concepts
Copy-number variants differ in frequency across genetic ancestry groups
Schultz L, Knighton A, Huguet G, Saci Z, Jean-Louis M, Mollon J, Knowles E, Glahn D, Jacquemont S, Almasy L. Copy-number variants differ in frequency across genetic ancestry groups. Human Genetics And Genomics Advances 2024, 5: 100340. PMID: 39138864, PMCID: PMC11401192, DOI: 10.1016/j.xhgg.2024.100340.
Peer-Reviewed Original Research
Concepts
Large‐scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 children and adolescents
Kurth F, Schijven D, van den Heuvel O, Hoogman M, van Rooij D, Stein D, Buitelaar J, Bölte S, Auzias G, Kushki A, Venkatasubramanian G, Rubia K, Bollmann S, Isaksson J, Jaspers‐Fayer F, Marsh R, Batistuzzo M, Arnold P, Bressan R, Stewart S, Gruner P, Sorensen L, Pan P, Silk T, Gur R, Cubillo A, Haavik J, Tuura R, Hartman C, Calvo R, McGrath J, Calderoni S, Jackowski A, Chantiluke K, Satterthwaite T, Busatto G, Nigg J, Gur R, Retico A, Tosetti M, Gallagher L, Szeszko P, Neufeld J, Ortiz A, Ghisleni C, Lazaro L, Hoekstra P, Anagnostou E, Hoekstra L, Simpson B, Plessen J, Deruelle C, Soreni N, James A, Narayanaswamy J, Reddy J, Fitzgerald J, Bellgrove M, Salum G, Janssen J, Muratori F, Vila M, Giral M, Ameis S, Bosco P, Remnélius K, Huyser C, Pariente J, Jalbrzikowski M, Rosa P, O'Hearn K, Ehrlich S, Mollon J, Zugman A, Christakou A, Arango C, Fisher S, Kong X, Franke B, Medland S, Thomopoulos S, Jahanshad N, Glahn D, Thompson P, Francks C, Luders E. Large‐scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 children and adolescents. Human Brain Mapping 2024, 45: e26754. PMID: 39046031, PMCID: PMC11267452, DOI: 10.1002/hbm.26754.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Neurostructural subgroup in 4291 individuals with schizophrenia identified using the subtype and stage inference algorithm
Jiang Y, Luo C, Wang J, Palaniyappan L, Chang X, Xiang S, Zhang J, Duan M, Huang H, Gaser C, Nemoto K, Miura K, Hashimoto R, Westlye L, Richard G, Fernandez-Cabello S, Parker N, Andreassen O, Kircher T, Nenadić I, Stein F, Thomas-Odenthal F, Teutenberg L, Usemann P, Dannlowski U, Hahn T, Grotegerd D, Meinert S, Lencer R, Tang Y, Zhang T, Li C, Yue W, Zhang Y, Yu X, Zhou E, Lin C, Tsai S, Rodrigue A, Glahn D, Pearlson G, Blangero J, Karuk A, Pomarol-Clotet E, Salvador R, Fuentes-Claramonte P, Garcia-León M, Spalletta G, Piras F, Vecchio D, Banaj N, Cheng J, Liu Z, Yang J, Gonul A, Uslu O, Burhanoglu B, Uyar Demir A, Rootes-Murdy K, Calhoun V, Sim K, Green M, Quidé Y, Chung Y, Kim W, Sponheim S, Demro C, Ramsay I, Iasevoli F, de Bartolomeis A, Barone A, Ciccarelli M, Brunetti A, Cocozza S, Pontillo G, Tranfa M, Park M, Kirschner M, Georgiadis F, Kaiser S, Van Rheenen T, Rossell S, Hughes M, Woods W, Carruthers S, Sumner P, Ringin E, Spaniel F, Skoch A, Tomecek D, Homan P, Homan S, Omlor W, Cecere G, Nguyen D, Preda A, Thomopoulos S, Jahanshad N, Cui L, Yao D, Thompson P, Turner J, van Erp T, Cheng W, Feng J. Neurostructural subgroup in 4291 individuals with schizophrenia identified using the subtype and stage inference algorithm. Nature Communications 2024, 15: 5996. PMID: 39013848, PMCID: PMC11252381, DOI: 10.1038/s41467-024-50267-3.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Brain‐age prediction: Systematic evaluation of site effects, and sample age range and size
Yu Y, Cui H, Haas S, New F, Sanford N, Yu K, Zhan D, Yang G, Gao J, Wei D, Qiu J, Banaj N, Boomsma D, Breier A, Brodaty H, Buckner R, Buitelaar J, Cannon D, Caseras X, Clark V, Conrod P, Crivello F, Crone E, Dannlowski U, Davey C, de Haan L, de Zubicaray G, Di Giorgio A, Fisch L, Fisher S, Franke B, Glahn D, Grotegerd D, Gruber O, Gur R, Gur R, Hahn T, Harrison B, Hatton S, Hickie I, Pol H, Jamieson A, Jernigan T, Jiang J, Kalnin A, Kang S, Kochan N, Kraus A, Lagopoulos J, Lazaro L, McDonald B, McDonald C, McMahon K, Mwangi B, Piras F, Rodriguez‐Cruces R, Royer J, Sachdev P, Satterthwaite T, Saykin A, Schumann G, Sevaggi P, Smoller J, Soares J, Spalletta G, Tamnes C, Trollor J, Ent D, Vecchio D, Walter H, Wang Y, Weber B, Wen W, Wierenga L, Williams S, Wu M, Zunta‐Soares G, Bernhardt B, Thompson P, Frangou S, Ge R, Group E. Brain‐age prediction: Systematic evaluation of site effects, and sample age range and size. Human Brain Mapping 2024, 45: e26768. PMID: 38949537, PMCID: PMC11215839, DOI: 10.1002/hbm.26768.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos
Xia R, Jian X, Rodrigue A, Bressler J, Boerwinkle E, Cui B, Daviglus M, DeCarli C, Gallo L, Glahn D, Knowles E, Moon J, Mosley T, Satizabal C, Sofer T, Tarraf W, Testai F, Blangero J, Seshadri S, González H, Fornage M. Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos. Alzheimer's & Dementia 2024, 20: 6070-6081. PMID: 38946675, PMCID: PMC11497725, DOI: 10.1002/alz.14082.
Peer-Reviewed Original Research
Concepts
A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels
de Vries P, Reventun P, Brown M, Heath A, Huffman J, Le N, Bebo A, Brody J, Temprano-Sagrera G, Raffield L, Ozel A, Thibord F, Jain D, Lewis J, Rodriguez B, Pankratz N, Taylor K, Polasek O, Chen M, Yanek L, Carrasquilla G, Marioni R, Kleber M, Trégouët D, Yao J, Li-Gao R, Joshi P, Trompet S, Martinez-Perez A, Ghanbari M, Howard T, Reiner A, Arvanitis M, Ryan K, Bartz T, Rudan I, Faraday N, Linneberg A, Ekunwe L, Davies G, Delgado G, Suchon P, Guo X, Rosendaal F, Klaric L, Noordam R, van Rooij F, Curran J, Wheeler M, Osburn W, O'Connell J, Boerwinkle E, Beswick A, Psaty B, Kolcic I, Souto J, Becker L, Hansen T, Doyle M, Harris S, Moissl A, Deleuze J, Rich S, van Hylckama Vlieg A, Campbell H, Stott D, Soria J, de Maat M, Almasy L, Brody L, Auer P, Mitchell B, Ben-Shlomo Y, Fornage M, Hayward C, Mathias R, Kilpeläinen T, Lange C, Cox S, März W, Morange P, Rotter J, Mook-Kanamori D, Wilson C, van der Harst P, Jukema J, Ikram M, Blangero J, Kooperberg C, Desch K, Johnson A, Sabater-Lleal M, Lowenstein C, Smith A, Morrison A, Abe N, Abecasis G, Aguet F, Albert C, Almasy L, Alonso A, Ament S, Anderson P, Anugu P, Applebaum-Bowden D, Ardlie K, Arking D, Arnett D, Ashley-Koch A, Aslibekyan S, Assimes T, Auer P, Avramopoulos D, Ayas N, Balasubramanian A, Barnard J, Barnes K, Barr R, Barron-Casella E, Barwick L, Beaty T, Beck G, Becker D, Becker L, Beer R, Beitelshees A, Benjamin E, Benos T, Bezerra M, Bielak L, Bis J, Blackwell T, Blangero J, Blue N, Boerwinkle E, Bowden D, Bowler R, Brody J, Broeckel U, Broome J, Brown D, Bunting K, Burchard E, Bustamante C, Buth E, Cade B, Cardwell J, Carey V, Carrier J, Carson A, Carty C, Casaburi R, Romero J, Casella J, Castaldi P, Chaffin M, Chang C, Chang Y, Chasman D, Chavan S, Chen B, Chen W, Chen Y, Cho M, Choi S, Chuang L, Chung M, Chung R, Clish C, Comhair S, Conomos M, Cornell E, Correa A, Crandall C, Crapo J, Cupples L, Curran J, Curtis J, Custer B, Damcott C, Darbar D, David S, Davis C, Daya M, de Andrade M, de las Fuentes L, de Vries P, DeBaun M, Deka R, DeMeo D, Devine S, Dinh H, Doddapaneni H, Duan Q, Dugan-Perez S, Duggirala R, Durda J, Dutcher S, Eaton C, Ekunwe L, Boueiz A, Ellinor P, Emery L, Erzurum S, Farber C, Farek J, Fingerlin T, Flickinger M, Fornage M, Franceschini N, Frazar C, Fu M, Fullerton S, Fulton L, Gabriel S, Gan W, Gao S, Gao Y, Gass M, Geiger H, Gelb B, Geraci M, Germer S, Gerszten R, Ghosh A, Gibbs R, Gignoux C, Gladwin M, Glahn D, Gogarten S, Gong D, Goring H, Graw S, Gray K, Grine D, Gross C, Gu C, Guan Y, Guo X, Gupta N, Haessler J, Hall M, Han Y, Hanly P, Harris D, Hawley N, He J, Heavner B, Heckbert S, Hernandez R, Herrington D, Hersh C, Hidalgo B, Hixson J, Hobbs B, Hokanson J, Hong E, Hoth K, Hsiung C, Hu J, Hung Y, Huston H, Hwu C, Irvin M, Jackson R, Jain D, Jaquish C, Johnsen J, Johnson C, Johnson A, Johnston R, Jones K, Kang H, Kaplan R, Kardia S, Kelly S, Kenny E, Kessler M, Khan A, Khan Z, Kim W, Kimoff J, Kinney G, Konkle B, Kooperberg C, Kramer H, Lange E, Lange L, Lange L, Laurie C, Laurie C, LeBoff M, Lee J, Lee S, Lee W, LeFaive J, Levine D, Levy D, Lewis J, Li X, Li Y, Lin H, Lin H, Lin X, Liu S, Liu Y, Liu Y, Loos R, Lubitz S, Lunetta K, Luo J, Magalang U, Mahaney M, Make B, Manichaikul A, Manning A, Manson J, Martin L, Marton M, Mathai S, Mathias R, May S, McArdle P, McDonald M, McFarland S, McGarvey S, McGoldrick D, McHugh C, McNeil B, Mei H, Meigs J, Menon V, Mestroni L, Metcalf G, Meyers D, Mignot E, Mikulla J, Min N, Minear M, Minster R, Mitchell B, Moll M, Momin Z, Montasser M, Montgomery C, Muzny D, Mychaleckyj J, Nadkarni G, Naik R, Naseri T, Natarajan P, Nekhai S, Nelson S, Neltner B, Nessner C, Nickerson D, Nkechinyere O, North K, O'Connell J, O'Connor T, Ochs-Balcom H, Okwuonu G, Pack A, Paik D, Palmer N, Pankow J, Papanicolaou G, Parker C, Peloso G, Peralta J, Perez M, Perry J, Peters U, Peyser P, Phillips L, Pleiness J, Pollin T, Post W, Becker J, Boorgula M, Preuss M, Psaty B, Qasba P, Qiao D, Qin Z, Rafaels N, Raffield L, Rajendran M, Ramachandran V, Rao D, Rasmussen-Torvik L, Ratan A, Redline S, Reed R, Reeves C, Regan E, Reiner A, Reupena M, Rice K, Rich S, Robillard R, Robine N, Roden D, Roselli C, Rotter J, Ruczinski I, Runnels A, Russell P, Ruuska S, Ryan K, Sabino E, Saleheen D, Salimi S, Salvi S, Salzberg S, Sandow K, Sankaran V, Santibanez J, Schwander K, Schwartz D, Sciurba F, Seidman C, Seidman J, Sériès F, Sheehan V, Sherman S, Shetty A, Shetty A, Sheu W, Shoemaker M, Silver B, Silverman E, Skomro R, Smith J, Smith J, Smith N, Smith T, Smith E, Smoller S, Snively B, Snyder M, Sofer T, Sotoodehnia N, Stilp A, Storm G, Streeten E, Su J, Sung Y, Sylvia J, Szpiro A, Taliun D, Tang H, Taub M, Taylor K, Taylor M, Taylor S, Telen M, Thornton T, Threlkeld M, Tinker L, Tirschwell D, Tishkoff S, Tiwari H, Tong C, Tracy R, Tsai M, Vaidya D, Van Den Berg D, VandeHaar P, Vrieze S, Walker T, Wallace R, Walts A, Wang F, Wang H, Wang J, Watson K, Watt J, Weeks D, Weinstock J, Weir B, Weiss S, Weng L, Wessel J, Willer C, Williams K, Williams L, Wilson J, Wilson J, Winterkorn L, Wong Q, Wu J, Xu H, Yanek L, Yang I, Yu K, Zekavat S, Zhang Y, Zhao S, Zhao W, Zhu X, Ziv E, Zody M, Zoellner S, Lindstrom S, Wang L, Smith N, Gordon W, van Hylckama Vlieg A, de Andrade M, Brody J, Pattee J, Haessler J, Brumpton B, Chasman D, Suchon P, Chen M, Turman C, Germain M, Wiggins K, MacDonald J, Braekkan S, Armasu S, Pankratz N, Jackson R, Nielsen J, Giulianini F, Puurunen M, Ibrahim M, Heckbert S, Bammler T, Frazer K, McCauley B, Taylor K, Pankow J, Reiner A, Gabrielsen M, Deleuze J, O'Donnell C, Kim J, McKnight B, Kraft P, Hansen J, Rosendaal F, Heit J, Psaty B, Tang W, Kooperberg C, Hveem K, Ridker P, Morange P, Johnson A, Kabrhel C, AlexandreTrégouët D, Smith N. A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels. Blood 2024, 143: 1845-1855. PMID: 38320121, DOI: 10.1182/blood.2023021452.
Peer-Reviewed Original Research
Concepts
434. Improving Image Accuracy in Low-Field Magnetic Resonance Imaging to Make Accessible Biomarkers for Psychiatric Disorders
Cooper R, Hayes R, Corcoran M, Sheth K, Arnold T, Stein J, Glahn D, Jalbrzikowski M. 434. Improving Image Accuracy in Low-Field Magnetic Resonance Imaging to Make Accessible Biomarkers for Psychiatric Disorders. Biological Psychiatry 2024, 95: s277-s278. DOI: 10.1016/j.biopsych.2024.02.933.
Peer-Reviewed Original Research
Concepts
409. Cortico-Thalamic Structural Co-Variation Networks are Related to Familial Risk for Schizophrenia in the Context of Lower Nuclei Volume Estimates in Patients: An ENIGMA Study
Lella A, Antonucci L, Weinberger D, Glahn D, Sim K, Gruber O, Chung Y, Sugranyes G, Clote E, Marcelis M, Kircher T, Van Rheenen T, Sponheim S, Dannlowski U, Iasevoli F, Pearlson G, Green M, Spalletta G, Lee T, Turner J, van Erp T, Thompson P, Bertolino A, Pergola G. 409. Cortico-Thalamic Structural Co-Variation Networks are Related to Familial Risk for Schizophrenia in the Context of Lower Nuclei Volume Estimates in Patients: An ENIGMA Study. Biological Psychiatry 2024, 95: s267-s268. DOI: 10.1016/j.biopsych.2024.02.908.
Peer-Reviewed Original Research
Concepts
417. Diagnostic Complexity, Symptomatology, and Functioning in Two Early-Onset Psychosis Family Studies: Epicenter and Epimex
Mollon J, Mathias S, Lanzagorta N, Rodrigue A, Knowles E, Deaso E, Cadavid L, Saavedra J, Phelps E, Polat N, Brownstein C, D’Angelo E, Deo A, Gonzalez-Heydrich J, Sarmiento E, Walsh C, Almasy L, Nicolini H, Glahn D. 417. Diagnostic Complexity, Symptomatology, and Functioning in Two Early-Onset Psychosis Family Studies: Epicenter and Epimex. Biological Psychiatry 2024, 95: s270-s271. DOI: 10.1016/j.biopsych.2024.02.916.
Peer-Reviewed Original Research
Concepts
8. The Relationship Between Treatment, Symptom Severity, and Brain Connectivity in Bipolar Disorder: An International Study Across 16 Enigma-Bipolar Sites
Nabulsi L, Kang M, Jahanshad N, Haarman B, McDonald C, Stein D, Glahn D, Pomarol-Clotet E, Vieta E, Houenou J, Favre P, Polosan M, Brambilla P, Bellani M, Mitchell P, Dannlowski U, Wessa M, Phillips M, Kircher T, Thompson P, Andreassen O, Ching C, Cannon D, Group E. 8. The Relationship Between Treatment, Symptom Severity, and Brain Connectivity in Bipolar Disorder: An International Study Across 16 Enigma-Bipolar Sites. Biological Psychiatry 2024, 95: s76-s77. DOI: 10.1016/j.biopsych.2024.02.186.
Peer-Reviewed Original Research
Concepts

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