2024
Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Varthi A, Rubio D, Grauer J. Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024 PMID: 39491749, DOI: 10.1016/j.spinee.2024.10.011.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsAdverse eventsPostoperative complicationsT2DM patientsCurrent Procedural TerminologyElixhauser Comorbidity IndexED visitsLumbar fusionHospital readmissionEmergency departmentOdds of postoperative complicationsNinety-day postoperative complicationsImpact of semaglutideOdds of hospital readmissionMonths of surgeryRetrospective cohort studyPostoperative adverse eventsMinor adverse eventsType II diabetes mellitusRisk of type I errorDiagnosis of T2DMII diabetes mellitusYears of ageInflammatory bowel disease is associated with greater odds of complications following posterior lumbar fusion and further amplified for patients exposed to biologics
Seddio A, Katsnelson B, Smith-Voudouris J, Gouzoulis M, Day W, Jabbouri S, Vasudevan R, Rubio D, Grauer J. Inflammatory bowel disease is associated with greater odds of complications following posterior lumbar fusion and further amplified for patients exposed to biologics. North American Spine Society Journal (NASSJ) 2024, 100574. DOI: 10.1016/j.xnsj.2024.100574.Peer-Reviewed Original ResearchPosterior lumbar fusionInflammatory bowel diseaseOdds ratioNational Inpatient SampleElixhauser Comorbidity IndexLumbar fusionBowel diseaseKaplan-Meier survival analysisEmergency departmentInflammatory bowel disease patientsLog-rank testMinor adverse eventsNon-IBD patientsIn-hospital dataMultivariate logistic regressionAssociated with greater oddsElevated odds ratiosReoperation rateSurgical complicationsSpine surgeryInferior outcomesPearlDiver databasePost-discharge outcomesAdult patientsAdverse eventsP31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Ratnasamy P, Rubio D, Grauer J. 35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients. The Spine Journal 2024, 24: s19. DOI: 10.1016/j.spinee.2024.06.478.Peer-Reviewed Original ResearchAdverse eventsSpinal neurologic deficitsStatistically significant differenceCurrent Procedural TerminologyElixhauser Comorbidity IndexEpidural injectionAdult patientsNeurological deficitsAdverse outcomesMultivariate analysisED visitsIncidence of adverse eventsEpidural spinal injectionsTransforaminal epidural injectionsEmergency departmentTransforaminal (TFRisk of adverse eventsSignificant differenceRetrospective cohort studyMinor adverse eventsSampled adult patientsOutcome measures IncidencePotential adverse eventsSpinal injectionPatient age100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetes
2023
Low Back Pain: Utilization of Urgent Cares Relative to Emergency Departments
Dhodapkar M, Modrak M, Halperin S, Gouzoulis M, Rubio D, Grauer J. Low Back Pain: Utilization of Urgent Cares Relative to Emergency Departments. Spine 2023, 49: 513-517. PMID: 37982595, DOI: 10.1097/brs.0000000000004880.Peer-Reviewed Original ResearchLow back painElixhauser Comorbidity IndexUrgent care centersEmergency departmentUrgent careBack painED visitsED utilizationCare centerAdvanced imagingUrgent care useUrgent care visitsDays of diagnosisSetting of traumaSpinal cord injuryYears of ageComorbidity indexInfectious diagnosisCare visitsLBP patientsMost patientsRecent surgeryAdult patientsPatient ageED patients