1998
Oncogenic activation of the PDGF β receptor by the transmembrane domain of p185neu*
Petti L, Irusta P, DiMaio D. Oncogenic activation of the PDGF β receptor by the transmembrane domain of p185neu*. Oncogene 1998, 16: 843-851. PMID: 9484775, DOI: 10.1038/sj.onc.1201590.Peer-Reviewed Original ResearchConceptsBa/F3 cellsTransmembrane domainBa/F3 hematopoietic cellsF3 cellsWild-type PDGF receptorNovel tyrosine phosphorylated proteinsIL-3-independent growthTyrosine phosphorylated proteinsDistinct signaling pathwaysWild-type PDGFLevels of phosphotyrosineWild-type receptorIL-3Β receptorPDGF β-receptorPhosphorylated proteinsTyrosine autophosphorylationOncogenic formsKinase activityMouse C127Receptor homodimerizationOncogenic activationSignaling pathwaysChimeric receptorsFoci formation
1995
An intact PDGF signaling pathway is required for efficient growth transformation of mouse C127 cells by the bovine papillomavirus E5 protein.
Riese D, DiMaio D. An intact PDGF signaling pathway is required for efficient growth transformation of mouse C127 cells by the bovine papillomavirus E5 protein. Oncogene 1995, 10: 1431-9. PMID: 7731695.Peer-Reviewed Original ResearchConceptsBPV E5 proteinPDGF beta receptorE5 proteinE5 geneC127 cellsBovine papillomavirus E5 proteinPDGF beta-receptor genePlatelet-derived growth factor beta receptorGrowth transformationBovine papillomavirus type 1 E5 proteinC127 cell linesMembrane-associated proteinsMouse C127 cellsHeterologous cell typesV-sis oncogeneDNA synthesisGrowth factor beta receptorStable growth transformationBeta receptor geneCell linesBeta receptorsBPV E5Reduced DNA synthesisMouse C127Genetic support
1993
Hierarchy of polyadenylation site usage by bovine papillomavirus in transformed mouse cells
Andrews E, DiMaio D. Hierarchy of polyadenylation site usage by bovine papillomavirus in transformed mouse cells. Journal Of Virology 1993, 67: 7705-7710. PMID: 7901430, PMCID: PMC238246, DOI: 10.1128/jvi.67.12.7705-7710.1993.Peer-Reviewed Original ResearchAnimalsAntisense Elements (Genetics)Base SequenceBovine papillomavirus 1Cell Transformation, ViralCells, CulturedCloning, MolecularConsensus SequenceDNA, ComplementaryMiceMolecular Sequence DataMutagenesisPoly APolymerase Chain ReactionRegulatory Sequences, Nucleic AcidRNA Processing, Post-TranscriptionalRNA, MessengerSequence Analysis, DNA
1991
Transforming Activity of Bovine and Human Papillomaviruses in Cultured Cells
DiMaio D. Transforming Activity of Bovine and Human Papillomaviruses in Cultured Cells. Advances In Cancer Research 1991, 56: 133-159. PMID: 1851373, DOI: 10.1016/s0065-230x(08)60480-7.Peer-Reviewed Original ResearchConceptsBovine papillomavirus type ICultured cellsTransient expression systemViral gene productsGene productsComplex phenotypesExpression systemTumorigenic transformationBiochemical eventsMolecular descriptionCell morphologyCottontail rabbit papillomavirusBiological responsesHuman carcinomasCultured fibroblastsGrowth propertiesCellsRabbit papillomavirusHomogeneous populationProfound effectGenesType ISimilar activityTumorigenesisPhenotype
1989
Bovine Papillomavirus Type I Induces Resistance to Ca++-Induced Terminal Differentiation in Murine Keratinocytes
Reiss M, DiMaio D, Zibello T. Bovine Papillomavirus Type I Induces Resistance to Ca++-Induced Terminal Differentiation in Murine Keratinocytes. Oncology Research Featuring Preclinical And Clinical Cancer Therapeutics 1989, 1: 75-82. PMID: 2561735, DOI: 10.3727/095535489820875318.Peer-Reviewed Original Research
1986
Nonsense mutation in open reading frame E2 of bovine papillomavirus DNA
DiMaio D. Nonsense mutation in open reading frame E2 of bovine papillomavirus DNA. Journal Of Virology 1986, 57: 475-480. PMID: 3003380, PMCID: PMC252759, DOI: 10.1128/jvi.57.2.475-480.1986.Peer-Reviewed Original ResearchConceptsMutant viral DNAOpen reading frame E2C127 cellsBovine papillomavirus DNAViral DNAGenetic mapping experimentsNonsense mutationMouse C127 cellsSingle base substitution mutationsHost cell genomeFull-length viral DNAFocus-forming activityBase substitution mutationsWild-type DNAAmber mutationCell genomeOncogenic transformationViral ORFsSubstitution mutationsORF E2Mapping experimentsMutant DNATransformation assaysDNABovine papillomavirus