Platelet-Derived Growth Factor Receptor Can Mediate Tumorigenic Transformation by the Bovine Papillomavirus E5 Protein
Nilson L, DiMaio D. Platelet-Derived Growth Factor Receptor Can Mediate Tumorigenic Transformation by the Bovine Papillomavirus E5 Protein. Molecular And Cellular Biology 1993, 13: 4137-4145. DOI: 10.1128/mcb.13.7.4137-4145.1993.Peer-Reviewed Original ResearchBovine papillomavirus type 1E5 proteinPlatelet-derived growth factor receptorPlatelet-derived growth factorBovine papillomavirus E5 proteinMurine mammary epithelial cell lineTumorigenic transformationIncreased tyrosine phosphorylationMammary epithelial cell lineWell-characterized roleSustained proliferative signalingMouse mammary glandPlatelet-derived growth factor receptor genesNMuMG cellsTransforming proteinTyrosine phosphorylationCellular proteinsE5 geneGrowth factor receptor pathwayEpidermal growth factor receptor pathwayEpithelial cell lineProliferative signalsB receptorSusceptible to transformationReceptor pathway