1992
The putative E5 open reading frame of cottontail rabbit papillomavirus is dispensable for papilloma formation in domestic rabbits
Brandsma J, Yang Z, DiMaio D, Barthold S, Johnson E, Xiao W. The putative E5 open reading frame of cottontail rabbit papillomavirus is dispensable for papilloma formation in domestic rabbits. Journal Of Virology 1992, 66: 6204-6207. PMID: 1326666, PMCID: PMC283673, DOI: 10.1128/jvi.66.10.6204-6207.1992.Peer-Reviewed Original ResearchConceptsE5 ORFCRPV DNACRPV genomeCottontail rabbit papillomavirusE5 mutantsFrameshift mutantsBiological functionsORFRabbit papillomavirusMutantsMutant DNATransition mutationsPapilloma formationDNA preparationsDNABiochemical analysisGenomeE5 regionDomestic rabbitsFrame mutationsMutationsCodonGenesInduction of papillomasFrameshift
1990
Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity
Riese D, Settleman J, Neary K, DiMaio D. Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity. Journal Of Virology 1990, 64: 944-949. PMID: 2153255, PMCID: PMC249196, DOI: 10.1128/jvi.64.2.944-949.1990.Peer-Reviewed Original ResearchConceptsRepressor proteinWild-type copy numberBovine papillomavirus type 1 genomeCopy numberViral genomeTranscriptional repressor proteinTransient expression experimentsMouse C127 cellsMutant viral DNAViral DNAType 1 genomeNumber phenotypeRepressor activityLow copy numberMethionine codonInitiation codonExpression experimentsC127 cellsGenomeCV1 cellsRepressor mutantsFoci formationColony formationCodonProtein
1987
Genetic and biochemical definition of the bovine papillomavirus E5 transforming protein.
Burkhardt A, DiMaio D, Schlegel R. Genetic and biochemical definition of the bovine papillomavirus E5 transforming protein. The EMBO Journal 1987, 6: 2381-2385. PMID: 2822390, PMCID: PMC553643, DOI: 10.1002/j.1460-2075.1987.tb02515.x.Peer-Reviewed Original ResearchConceptsFirst methionine codonMethionine codonE5 proteinCellular membranesAmino-terminal mutationsFrameshift mutationBovine papillomavirus E5Mutant viral genomesCellular transformationInitiation codonHydrophobic polypeptidesBPV genomeSmall polypeptidesCell transformationCodonViral genomeE5 ORFProteinBovine papillomavirusGenetic alterationsMutationsPolypeptideForm dimersGenomeFrame mutations