Daniel Barson, PhD
About
Biography
Daniel is an MD/PhD candidate working with Michael Crair and Michael Higley in the Department of Neuroscience. His research is at the interface of cellular and systems neuroscience, developing novel imaging methods to understand how large-scale patterns of brain activity influence the firing of individual or groups of neurons and how these patterns of activity change across development and subserve behavior. Prior to coming to Yale, he received an AB from Princeton University and an MPhil from University of Cambridge, where he discovered his interest in cellular and systems neuroscience. When not in lab or on the wards, he can be found being walked around the East Rock neighborhood by his dog, Leo, or exploring new hiking trails throughout New England.
Education & Training
- PhD
- Yale University, Interdepartmental Neuroscience Program (2022)
- MPhil
- University of Cambridge, Clinical Neurosciences (2013)
- AB
- Princeton University, Molecular Biology (2012)
Research
Research at a Glance
Yale Co-Authors
Publications Timeline
Michael Crair, PhD
Michael J Higley, MD/PhD
Corey Horien
Dustin Scheinost, PhD, BS
Jessica Cardin, PhD
Joseph Santos-Sacchi, PhD
Publications
2024
Hebbian instruction of axonal connectivity by endogenous correlated spontaneous activity
Matsumoto N, Barson D, Liang L, Crair M. Hebbian instruction of axonal connectivity by endogenous correlated spontaneous activity. Science 2024, 385: eadh7814. PMID: 39146415, DOI: 10.1126/science.adh7814.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSpontaneous activitySpontaneous retinal wavesAxonal connectionsPatterns of correlated activityNeonatal miceEvidence in vivoRetinal wavesPostsynaptic neuronsNeuronal activityIn vivoAxonal arborsAxonal processesAxonsRetinocollicular axonsNeural connectionsIndividual axonsMorphological changesSubcellular precisionEndogenous pattern
2023
Why is everyone talking about brain state?
Greene A, Horien C, Barson D, Scheinost D, Constable R. Why is everyone talking about brain state? Trends In Neurosciences 2023, 46: 508-524. PMID: 37164869, PMCID: PMC10330476, DOI: 10.1016/j.tins.2023.04.001.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords
2021
Efferent feedback controls bilateral auditory spontaneous activity
Wang Y, Sanghvi M, Gribizis A, Zhang Y, Song L, Morley B, Barson DG, Santos-Sacchi J, Navaratnam D, Crair M. Efferent feedback controls bilateral auditory spontaneous activity. Nature Communications 2021, 12: 2449. PMID: 33907194, PMCID: PMC8079389, DOI: 10.1038/s41467-021-22796-8.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSpontaneous activityEfferent modulationEfferent pathwaysMedial olivocochlear systemCentral nervous systemCentral auditory systemInner hair cellsAuditory systemNicotinic acetylcholine receptorsSpontaneous activity patternsOlivocochlear systemHearing onsetEfferent systemChemogenetic experimentsBilateral couplingNervous systemAcetylcholine receptorsCircuit formationEfferent feedbackFiring patternsHair cellsΑ9/Auditory sensitivityBilateral correlationActivity patterns
2019
Simultaneous mesoscopic and two-photon imaging of neuronal activity in cortical circuits
Barson D, Hamodi AS, Shen X, Lur G, Constable RT, Cardin JA, Crair MC, Higley MJ. Simultaneous mesoscopic and two-photon imaging of neuronal activity in cortical circuits. Nature Methods 2019, 17: 107-113. PMID: 31686040, PMCID: PMC6946863, DOI: 10.1038/s41592-019-0625-2.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsVasoactive intestinal peptide-expressing interneuronsBrain-wide network dynamicsTwo-photon calcium imagingEntire cortical mantleLocal neuronal circuitsLong-range cortical networksWidespread gene deliveryWidefield calciumPyramidal neuronsAwake miceCortical circuitsNeuronal activityCortical mantleTwo-photon imagingViral transduction methodsNeuronal circuitsCalcium imagingMouse brainFunctional connectivityLocal microcircuitsMammalian cortexCortical architectureCortical networksBrainActivity propagates
2017
Multiscale optical imaging of cortical activity in mouse
Barson D, Hamodi A, Lur G, Cardin J, Crair M, Higley M. Multiscale optical imaging of cortical activity in mouse. 2017, jtu4a.13. DOI: 10.1364/boda.2017.jtu4a.13.Peer-Reviewed Original Research
2014
Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression.
Tyzack GE, Sitnikov S, Barson D, Adams-Carr KL, Lau NK, Kwok JC, Zhao C, Franklin RJ, Karadottir RT, Fawcett JW, Lakatos A. Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression. Nature Communications 2014, 5: 4294. PMID: 25014177, PMCID: PMC4104454, DOI: 10.1038/ncomms5294.Peer-Reviewed Original Research
News
News
- September 28, 2020
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