Comparative functional genomics identifies unique molecular features of EPSCs
Malik V, Zang R, Fuentes-Iglesias A, Huang X, Li D, Fidalgo M, Zhou H, Wang J. Comparative functional genomics identifies unique molecular features of EPSCs. Life Science Alliance 2022, 5: e202201608. PMID: 35961778, PMCID: PMC9378845, DOI: 10.26508/lsa.202201608.Peer-Reviewed Original ResearchConceptsEmbryonic stem cellsProteome of embryonic stem cellsComparative functional genomicsHistone modification marksChromatin accessibility featuresModification marksChromatin accessibilityFunctional genomicsRegulatory networksTranslational regulationPluripotency factors OCT4Molecular foundationMaintenance in vitroMolecular underpinningsTotipotent stem cellsMolecular signaturesChromatinFactors Oct4Stem cellsDevelopmental potencySelf-renewalMolecular featuresGenomeCellsTranscriptome