2024
Epigenome-Wide Association Study of Depressive Symptoms in Black Women in the InterGEN Study
Taylor B, Zhao Y, Perez N, Potts-Thompson S, Crusto C, Creber R, Taylor J. Epigenome-Wide Association Study of Depressive Symptoms in Black Women in the InterGEN Study. International Journal Of Molecular Sciences 2024, 25: 7681. PMID: 39062924, PMCID: PMC11277114, DOI: 10.3390/ijms25147681.Peer-Reviewed Original ResearchDepressive symptomsPerceived discriminationSuch as low socioeconomic statusBlack womenIncreased risk of depressionStudies of depressive symptomsSecondary analysis of dataBeck Depression InventoryPrevalence of depressionRisk of depressionLow socioeconomic statusExperiences of discriminationInterGEN StudyDepression InventoryDNA methylation sitesSocioeconomic statusEvent ScalePsychosocial stressorsSecondary analysisDepressionDNA methylationEpigenome-wide association studiesPsychological factorsAnalysis of dataIncreased risk
2022
Epigenome‐wide association study of BMI in Black populations from InterGEN and GENOA
Taylor J, Huang Y, Zhao W, Wright M, Wang Z, Hui Q, Potts‐Thompson S, Barcelona V, Prescott L, Yao Y, Crusto C, Kardia S, Smith J, Sun Y. Epigenome‐wide association study of BMI in Black populations from InterGEN and GENOA. Obesity 2022, 31: 243-255. PMID: 36479596, PMCID: PMC10107734, DOI: 10.1002/oby.23589.Peer-Reviewed Original ResearchConceptsObesity-associated conditionsSignificant public health concernAssociation of BMIPeripheral blood samplesLinear mixed-effects regression modelsBlack populationPublic health concernMixed-effects regression modelsBlack womenCross-sectional analysisEpigenome-wide DNA methylationIllumina EPIC BeadChipDevelopment of diseaseCardiometabolic disordersDiscovery cohortBlood samplesBMIHigh incidenceEarly onsetGENOA studyObesityHealth concernCohortDNAm sitesDNA methylationThe Interaction of Trauma Exposure and DNA Methylation on Blood Pressure Among Black Women in the InterGEN Study
Caceres B, Huang Y, Barcelona V, Wang Z, Newhall K, Cerdeña J, Crusto C, Sun Y, Taylor J. The Interaction of Trauma Exposure and DNA Methylation on Blood Pressure Among Black Women in the InterGEN Study. Epigenetics Insights 2022, 15: 25168657221138510. PMID: 36466626, PMCID: PMC9716582, DOI: 10.1177/25168657221138510.Peer-Reviewed Original ResearchDiastolic blood pressureBlood pressureTrauma exposureHypertension riskBody mass indexChildhood traumaEpigenome-wide significance levelBlack mothersBlack womenSeparate linear mixed-effects modelsMass indexCigarette smokingMean ageHigh riskLinear mixed effects modelsBlack adultsTraumaDNA methylationVicarious traumaEpigenetic mechanismsCpG sitesMixed effects models