2007
An Inflammatory Pathway of IFN-γ Production in Coronary Atherosclerosis
Ranjbaran H, Sokol SI, Gallo A, Eid RE, Iakimov AO, D’Alessio A, Kapoor JR, Akhtar S, Howes CJ, Aslan M, Pfau S, Pober JS, Tellides G. An Inflammatory Pathway of IFN-γ Production in Coronary Atherosclerosis. The Journal Of Immunology 2007, 178: 592-604. PMID: 17182600, DOI: 10.4049/jimmunol.178.1.592.Peer-Reviewed Original ResearchConceptsIL-12/ILIFN-gamma-inducible chemokinesCoronary atherosclerosisIL-12IL-18IFN-gammaPlasma levelsT cellsTh1-type cytokine productionHuman atherosclerotic coronary arteriesAcute coronary syndromeSubset of patientsHuman coronary atherosclerosisTh1-type cytokinesC-reactive proteinIFN-γ productionElevated plasma levelsPlasma of patientsInnate immune responseAtherosclerotic coronary arteriesCoronary syndromeSystemic inflammationCardiac catheterizationCardiopulmonary bypassGamma secretion
2004
Comparison of coronary artery specific leukocyte–platelet conjugate formation in unstable versus stable angina pectoris
Patel PB, Pfau SE, Cleman MW, Brennan JJ, Howes C, Remetz M, Cabin HS, Setaro JF, Rinder HM. Comparison of coronary artery specific leukocyte–platelet conjugate formation in unstable versus stable angina pectoris. The American Journal Of Cardiology 2004, 93: 410-413. PMID: 14969612, DOI: 10.1016/j.amjcard.2003.10.033.Peer-Reviewed Original ResearchConceptsNeutrophil-platelet conjugatesPlatelet activationAngina pectorisCoronary angiographyCoronary sinusLeukocyte-platelet conjugatesDiagnostic coronary angiographyStable angina pectorisCoronary artery diseaseChest painArtery diseaseCardiac catheterizationCoronary arteryCoronary circulationCoronary bedAortic rootBlood samplesPatientsMonocyte-platelet bindingPectorisSimilar degreeAngiographySinusActivation stateNeutrophils