2019
Preserving the balance: diverse forms of long-term GABAergic synaptic plasticity
Chiu CQ, Barberis A, Higley MJ. Preserving the balance: diverse forms of long-term GABAergic synaptic plasticity. Nature Reviews Neuroscience 2019, 20: 272-281. PMID: 30837689, DOI: 10.1038/s41583-019-0141-5.Peer-Reviewed Original ResearchConceptsGABAergic synaptic plasticityInhibitory GABAergic synapsesPostsynaptic action potentialsInhibitory synaptic strengthGABAergic synapsesSynaptic excitationLong-term plasticityGlutamatergic signalingNeuronal activitySynaptic plasticityNeuronal circuitsAction potentialsSynaptic strengthIndividual neuronsCellular mechanismsLines of evidenceBody of literaturePlasticityNeuronsFunctional stabilitySynapses
2013
Compartmentalization of GABAergic Inhibition by Dendritic Spines
Chiu CQ, Lur G, Morse TM, Carnevale NT, Ellis-Davies GC, Higley MJ. Compartmentalization of GABAergic Inhibition by Dendritic Spines. Science 2013, 340: 759-762. PMID: 23661763, PMCID: PMC3752161, DOI: 10.1126/science.1234274.Peer-Reviewed Original ResearchConceptsGABAergic inhibitionDendritic spinesPerisomatic inhibitory synapsesPyramidal cell dendritesTwo-photon calcium imagingAction potential outputAcid-mediated inhibitionIndividual dendritic spinesGABAergic controlGABAergic synapsesPyramidal neuronsCell dendritesInhibitory synapsesNeuronal activityCalcium imagingSpine headsInhibitory actionNeocortexInhibitionSpineSynapsesCompartmentalized controlCritical roleSignalingPostsynaptic
2001
Spontaneous Activity in Developing Ferret Visual Cortex In Vivo
Chiu C, Weliky M. Spontaneous Activity in Developing Ferret Visual Cortex In Vivo. Journal Of Neuroscience 2001, 21: 8906-8914. PMID: 11698602, PMCID: PMC6762264, DOI: 10.1523/jneurosci.21-22-08906.2001.Peer-Reviewed Original ResearchConceptsLateral geniculate nucleusVisual cortex in vivoVisual cortexSpontaneous activityPatterns of correlated activityTiming of spiking activityPatterns of spontaneous activityCortex in vivoExtracellular neuronal activityGeniculate nucleusLong-rangePostnatal dayExtracellular recordingsSpike activityNeuronal activityCross-correlation analysisIntrinsic circuitsSynchronous burstsCortical sitesCortexRecording sitesEye openingCorrelated activityAnatomical organizationPatchy organization