2009
Designer DNA Nanoarchitectures
Lin C, Liu Y, Yan H. Designer DNA Nanoarchitectures. Biochemistry 2009, 48: 1663-1674. PMID: 19199428, PMCID: PMC2765550, DOI: 10.1021/bi802324w.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStructural DNA nanotechnologyDNA nanotechnologyDNA nanoarchitecturesSelf-assembled architecturesWatson-Crick base pairing rulesProtein-protein interactionsBase pairing rulesDNA nanostructuresMulticomponent nanomachinesPrinciples of DNAArtificial nanostructuresNanometer precisionHelical DNA structureUnicellular diatomsFunctional groupsDNA structureNanotechnologyNanostructuresMolecular speciesNanoarchitecturesSuch eleganceExciting progressHigh yieldsBiological systemsDNA
2008
Signal amplification on a DNA-tile-based biosensor with enhanced sensitivity
Lin C, Nangreave JK, Li Z, Liu Y, Yan H. Signal amplification on a DNA-tile-based biosensor with enhanced sensitivity. Nanomedicine 2008, 3: 521-528. PMID: 18694314, DOI: 10.2217/17435889.3.4.521.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateBiosensing TechniquesDNADNA, ViralNanotechnologyReproducibility of ResultsSevere acute respiratory syndrome-related coronavirusConceptsHybridization chain reactionSignal amplificationSelf-assembled DNAMultiplexed biosensingFluorescence enhancementNanomedical applicationsSensitive detectionDetection probeConfocal fluorescence microscopySignal amplifierImprovement of sensitivityDetection sensitivityOrders of magnitudeEnhanced sensitivityBiosensorBiosensingFluorescence microscopyNanoarraysSuccessful detectionReactionMicroscopyVersatilityDetection targetProbeDetection