2022
Actuating tension-loaded DNA clamps drives membrane tubulation
Liu L, Xiong Q, Xie C, Pincet F, Lin C. Actuating tension-loaded DNA clamps drives membrane tubulation. Science Advances 2022, 8: eadd1830. PMID: 36223466, PMCID: PMC9555772, DOI: 10.1126/sciadv.add1830.Peer-Reviewed Original ResearchConceptsDNA clampMembrane tubulationMembrane dynamicsMembrane-remodeling eventsVesicle tubulationConformational changesSpatiotemporal controlDNA signalsCell membraneDNA nanostructuresTubulationMembrane deformationClosed stateOpen stateSelf-assembled DNA nanostructuresOrganismsProteinMembrane tubeArtificial systemsTube widthMembraneDynamics
2020
DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells
Williams ND, Landajuela A, Kasula RK, Zhou W, Powell JT, Xi Z, Isaacs FJ, Berro J, Toomre D, Karatekin E, Lin C. DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells. Nano Letters 2020, 20: 8890-8896. PMID: 33164530, PMCID: PMC7726105, DOI: 10.1021/acs.nanolett.0c03925.Peer-Reviewed Original ResearchConceptsCopies of proteinsBrightness standardsFluorescence microscopyProtein countingMammalian cellsFluorescent proteinCopy numberLive cellsConventional quantification techniquesBiological LaboratoryFluorescence microscopeProteinDNA origamiVersatile toolCellsBiologyCurrent quantification methodsCopiesOrganic dyes
2006
DNA Tile Based Self‐Assembly: Building Complex Nanoarchitectures
Lin C, Liu Y, Rinker S, Yan H. DNA Tile Based Self‐Assembly: Building Complex Nanoarchitectures. ChemPhysChem 2006, 7: 1641-1647. PMID: 16832805, DOI: 10.1002/cphc.200600260.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDNA tilesSelf-assembled DNA nanostructuresNanometer-scale materialsNanometer-scale componentsComplex nanoarchitecturesDNA nanostructuresNanophotonic devicesAttractive routeExcellent scaffoldProgrammable patternsNanoarchitecturesPotential applicationsExciting progressNanoarraysNanoparticlesNanostructuresRecent developmentsScaffoldsDevicesRouteMaterials