1736-P: Exploring Intrinsic Features of Human Pancreatic a- and ß-Cell Physiology Using Pseudoislets
ROZO A, ROMAN J, QIN W, LIU C, NAJI A, KAESTNER K, HOSHI T, STOFFERS D, DOLIBA N. 1736-P: Exploring Intrinsic Features of Human Pancreatic a- and ß-Cell Physiology Using Pseudoislets. Diabetes 2024, 73 DOI: 10.2337/db24-1736-p.Peer-Reviewed Original ResearchB cell physiologyIslet cell typesCell typesOxygen consumption rateA cellsCa2+ fluxBaseline oxygen consumption rateIntrinsic cellular functionsGlucose-mediated inhibitionCellular functionsNative isletsPancreatic AEffect of glucoseMitochondrial functionResponse to glucoseAmino acidsRate of secretionGenetic interventionsPseudoisletsB cell aggregatesGlucose-induced inhibitionHuman APhysiologyCell populationsIslets