Beagle pup model of brain injury: regional cerebral blood flow and cerebral prostaglandins.
Ment L, Stewart W, Duncan C, Pitt B, Cole J. Beagle pup model of brain injury: regional cerebral blood flow and cerebral prostaglandins. Journal Of Neurosurgery 1987, 67: 278-83. PMID: 3598687, DOI: 10.3171/jns.1987.67.2.0278.Peer-Reviewed Original ResearchConceptsRegional cerebral blood flowCerebral blood flowAsphyxial insultBrain injuryBlood flowSevere asphyxial insultPeriventricular white matterSevere brain injuryRole of prostaglandinsEffects of asphyxiaNewborn beagle pupsCerebral prostaglandinsVentilatory supportNeuropathological changesPGE2 levelsCommon causeBeagle pupsWhite matterAutoradiographic determinationInsultPupsAsphyxiaYoung childrenSeparate groupsSignificant increase