1986
Beagle puppy model of perinatal cerebral insults. Cerebral blood flow changes and intraventricular hemorrhage evoked by hypoxemia.
Ment L, Stewart W, Duncan C, Pitt B. Beagle puppy model of perinatal cerebral insults. Cerebral blood flow changes and intraventricular hemorrhage evoked by hypoxemia. Journal Of Neurosurgery 1986, 65: 847-50. PMID: 3772483, DOI: 10.3171/jns.1986.65.6.0847.Peer-Reviewed Original ResearchConceptsCerebral blood flowWhite matterIntraventricular hemorrhageRegional cerebral blood flowCerebral blood flow changesNeonatal cerebral infarctionPerinatal cerebral insultsParieto-occipital white matterEffects of hypoxemiaBeagle puppy modelNewborn beagle pupsBlood flow changesTemporal white matterParietal white matterCentral gray regionNeuropathological injuryCerebral infarctionPerinatal asphyxiaCerebral insultNeuropathological changesPuppy modelCommon causeGerminal matrixBeagle pupsBlood flowBeagle puppy model of perinatal cerebral infarction. Regional cerebral prostaglandin changes during acute hypoxemia.
Ment L, Stewart W, Duncan C, Pitt B, Cole J. Beagle puppy model of perinatal cerebral infarction. Regional cerebral prostaglandin changes during acute hypoxemia. Journal Of Neurosurgery 1986, 65: 851-5. PMID: 3772484, DOI: 10.3171/jns.1986.65.6.0851.Peer-Reviewed Original ResearchConceptsCerebral blood flowPerinatal cerebral infarctionPeriventricular white matterCerebral infarctionHypoxemic insultWhite matterStable metaboliteGray matterLocal cerebral blood flowArterial blood pressureEffects of hypoxemiaBeagle puppy modelNewborn beagle pupsSignificant differencesAcute hypoxemiaProstaglandin changesNeuropathological alterationsBlood pressureIndwelling catheterNeuropathological changesIntensive carePuppy modelUncommon findingProstaglandin levelsCommon causeBacterial meningitis as an etiology of perinatal cerebral infarction
Ment L, Ehrenkranz R, Duncan C. Bacterial meningitis as an etiology of perinatal cerebral infarction. Pediatric Neurology 1986, 2: 276-279. PMID: 3508700, DOI: 10.1016/0887-8994(86)90019-6.Peer-Reviewed Original ResearchConceptsBacterial meningitisCerebral infarctionNewborn Special Care UnitPerinatal cerebral infarctionSpecial care unitsMonths of ageEarly intervention servicesNeurodevelopmental sequelaeNeuropathologic studiesCare unitTomographic scanSecondary edemaNeonatal scansSignificant incidenceMortality rateVascular distributionMeningitisInfarctionIntervention servicesSubsequent scansNeonatesTomographic studiesScansMonthsSignificant improvement
1985
Beagle puppy model of perinatal cerebral infarction. Acute changes in regional cerebral prostaglandins during hemorrhagic hypotension.
Ment L, Stewart W, Duncan C, Cole J, Pitt B. Beagle puppy model of perinatal cerebral infarction. Acute changes in regional cerebral prostaglandins during hemorrhagic hypotension. Journal Of Neurosurgery 1985, 63: 899-904. PMID: 4056903, DOI: 10.3171/jns.1985.63.6.0899.Peer-Reviewed Original ResearchConceptsPerinatal cerebral infarctionPeriventricular white matterNewborn beagle pupsHemorrhagic hypotensionWhite matterCerebral infarctionNeuropathological changesThromboxane B2Beagle pupsMean arterial blood pressureSlow venous hemorrhagePeriventricular white matter regionsArterial blood pressureProstaglandin E2 levelsEffects of hypotensionCerebral blood flowProstaglandin determinationsBeagle puppy modelStable breakdown productWhite matter regionsCerebral prostaglandinsBlood pressureIntensive carePuppy modelPGF1 alphaBeagle puppy model of perinatal cerebral infarction. Acute changes in cerebral blood flow and metabolism during hemorrhagic hypotension.
Ment L, Stewart W, Duncan C, Pitt B, Rescigno A, Cole J. Beagle puppy model of perinatal cerebral infarction. Acute changes in cerebral blood flow and metabolism during hemorrhagic hypotension. Journal Of Neurosurgery 1985, 63: 441-7. PMID: 3839525, DOI: 10.3171/jns.1985.63.3.0441.Peer-Reviewed Original ResearchConceptsLocal cerebral glucose utilizationCerebral blood flowRegional cerebral blood flowHypotensive insultCerebral infarctionHemorrhagic hypotensionBlood flowUncoupling of CBFMean arterial blood pressureNeonatal cerebral infarctionParieto-occipital white matterPerinatal cerebral infarctionSerum prostaglandin levelsSlow venous hemorrhagePeriventricular white matter regionsAutoradiographic determinationArterial blood pressureCerebral glucose utilizationProstaglandin E2 levelsEffects of hypotensionBeagle puppy modelNewborn beagle pupsGray matter structuresStable breakdown productWhite matter regions1691 ASSOCIATION OF CEREBRAL PROSTAGLANDIN IMBALANCE WITH PERINMAL STROKE
Ment L, Duncan C, Stewart W, Pitt B, Cole J, Pearson H. 1691 ASSOCIATION OF CEREBRAL PROSTAGLANDIN IMBALANCE WITH PERINMAL STROKE. Pediatric Research 1985, 19: 392-392. DOI: 10.1203/00006450-198504000-01715.Peer-Reviewed Original ResearchCerebral blood flowNewborn beagle pupsCerebral infarctionBeagle pupsBlood flowPGI2/TXA2 balanceNeonatal cerebral infarctionSlow venous hemorrhageStable breakdown productPerinatal ischemiaNeuropathological consequencesProstaglandin levelsCommon causeVenous hemorrhageHH groupSimilar insultsStable metaboliteEffects of HhPG levelsC groupInsultPupsInfarctionMABPHgPerinatal Cerebral Insults: Hemorrhage and Ischemia
Ment L, Duncan C, Stewart W. Perinatal Cerebral Insults: Hemorrhage and Ischemia. Pediatric Neurosurgery 1985, 12: 168-174. PMID: 3916368, DOI: 10.1159/000120242.Peer-Reviewed Original ResearchConceptsMajor neurodevelopmental handicapsCerebral blood flowNeurodevelopmental handicapParenchymal involvementCerebral infarctionPreterm infantsIntraventricular hemorrhageGestational ageIschemic insultPerinatal careHigh riskBlood flowHemorrhageInfantsDevelopmental abnormalitiesCareInfarctionIschemiaNeonatesLesionsAbnormalitiesIncidenceInsultSurvivorsBrain
1984
Perinatal cerebral infarction
Ment L, Duncan C, Ehrenkranz R. Perinatal cerebral infarction. Annals Of Neurology 1984, 16: 559-568. PMID: 6508239, DOI: 10.1002/ana.410160506.Peer-Reviewed Original ResearchConceptsPerinatal cerebral infarctionCerebral infarctionNeonatal intraventricular hemorrhageFull-term infantsMonths of ageTwelve-month intervalsPerinatal asphyxiaPreterm neonatesIntraventricular hemorrhageNeonatal seizuresTomographic scanCommon causePostmortem examinationInfarctionInfantsStrokeAsphyxiaHemorrhageNeonatesSeizuresUteroDiagnosisMonths