2005
Are Racial and Ethnic Minorities Less Willing to Participate in Health Research?
Wendler D, Kington R, Madans J, Van Wye G, Christ-Schmidt H, Pratt LA, Brawley OW, Gross CP, Emanuel E. Are Racial and Ethnic Minorities Less Willing to Participate in Health Research? PLOS Medicine 2005, 3: e19. PMID: 16318411, PMCID: PMC1298944, DOI: 10.1371/journal.pmed.0030019.Peer-Reviewed Original ResearchConceptsOverall consent rateNon-Hispanic whitesConsent ratesHealth research studiesHealth researchAfrican AmericansClinical intervention studiesResearch enrollment decisionsNon-minority individualsComprehensive literature searchNon-intervention studySingle-site studyConcorde studySurgery TrialSurgical trialsDrug treatmentIntervention studiesMulti-site studyUS sitesLiterature searchEthnic minoritiesDelta studyVast majorityWillingness of minoritiesHispanics
2004
Participation in Cancer Clinical Trials: Race-, Sex-, and Age-Based Disparities
Murthy VH, Krumholz HM, Gross CP. Participation in Cancer Clinical Trials: Race-, Sex-, and Age-Based Disparities. JAMA 2004, 291: 2720-2726. PMID: 15187053, DOI: 10.1001/jama.291.22.2720.Peer-Reviewed Original ResearchConceptsCancer trialsCancer clinical trialsClinical trialsTrial participantsEnrollment fractionWhite patientsAge groupsCross-sectional population-based analysisProstate cancer clinical trialsCancer research participationCancer trial participantsColorectal cancer trialsPatients 75 yearsIncident cancer patientsLung cancer trialsPopulation-based analysisRelative risk ratiosAge-based disparitiesYears of ageNational Cancer InstituteLogistic regression modelsLittle recent informationTrial enrolleesYounger patientsPatient group