2024
Sex‐specific topological structure associated with dementia via latent space estimation
Wang S, Wang Y, Xu F, Tian X, Fredericks C, Shen L, Zhao Y, Initiative F. Sex‐specific topological structure associated with dementia via latent space estimation. Alzheimer's & Dementia 2024 PMID: 39530632, DOI: 10.1002/alz.14266.Peer-Reviewed Original Research
2022
Sex differences in default mode network connectivity in healthy aging adults
Ficek-Tani B, Horien C, Ju S, Xu W, Li N, Lacadie C, Shen X, Scheinost D, Constable T, Fredericks C. Sex differences in default mode network connectivity in healthy aging adults. Cerebral Cortex 2022, 33: 6139-6151. PMID: 36563018, PMCID: PMC10183749, DOI: 10.1093/cercor/bhac491.Peer-Reviewed Original ResearchConceptsDefault mode networkPreclinical Alzheimer's diseaseAlzheimer's diseaseSex differencesBrain connectivity changesDefault mode network connectivityIntrinsic connectivity distributionSeed-based analysisMode network connectivityMedial prefrontal cortexPosterior DMN nodesHealthy aging adultsImpact of sexLifetime riskDMN connectivityWhole brainPosterior cingulateDMN nodesSignificant sex differencesPrefrontal cortexConnectivity changesAging AdultsHealthy participantsDMN functionMode network
2018
Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar?
Fredericks CA, Brown JA, Deng J, Kramer A, Ossenkoppele R, Rankin K, Kramer JH, Miller BL, Rabinovici GD, Seeley WW. Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar? NeuroImage Clinical 2018, 21: 101628. PMID: 30528957, PMCID: PMC6411779, DOI: 10.1016/j.nicl.2018.101628.Peer-Reviewed Original ResearchConceptsPosterior cortical atrophyVisuospatial networkAlzheimer's diseaseClinical featuresCortical atrophyPulvinar nucleusSN connectivityConnectivity changesPulvinar thalamic nucleiPatients' clinical featuresAmnestic Alzheimer's diseaseMedial pulvinar nucleusLateral pulvinar nucleusDefault mode network connectivitySalience network connectivityMore depressive symptomsMode network connectivityStandardized neuropsychological batteryTask-free fMRIIntrinsic connectivity networksDirect anatomical connectionsVisuospatial symptomsConnectivity increasesBrain atrophyPCa patients