2023
Evaluation of potential instruments for quantifying necrobiosis lipoidica severity via physician evaluation and patient-reported outcomes
Hashemi D, Nelson C, Nyberg M, Das M, Rosenbach M. Evaluation of potential instruments for quantifying necrobiosis lipoidica severity via physician evaluation and patient-reported outcomes. Journal Of The American Academy Of Dermatology 2023, 89: 1305-1306. PMID: 37633461, DOI: 10.1016/j.jaad.2023.08.048.Peer-Reviewed Original ResearchAssessing the Discriminatory Ability of Diagnostic Criteria for Ulcerative Pyoderma Gangrenosum and Its Mimickers
Ji-Xu A, Liakos W, Merleev A, Brüggen M, Nelson C. Assessing the Discriminatory Ability of Diagnostic Criteria for Ulcerative Pyoderma Gangrenosum and Its Mimickers. JAMA Dermatology 2023, 159: 337-338. PMID: 36652229, PMCID: PMC9857708, DOI: 10.1001/jamadermatol.2022.5978.Peer-Reviewed Original ResearchIdentification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with Sweet syndrome
Bhattacharya S, Basu S, Sheng E, Murphy C, Wei J, Kersh A, Nelson C, Bryer J, Ashchyan H, Steele K, Forrestel A, Seykora J, Micheletti R, James W, Rosenbach M, Leung T. Identification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with Sweet syndrome. Journal Of Clinical Investigation 2023, 133: e162137. PMID: 36355435, PMCID: PMC9797331, DOI: 10.1172/jci162137.Peer-Reviewed Original ResearchConceptsSteroid-sparing agentSweet's syndromeInflammatory diseasesCorticosteroid-related side effectsElevated IL-1Febrile neutrophilic dermatosisDramatic therapeutic responseReceptor 1 antagonistNeutrophil respiratory burstMultiorgan inflammatory diseasePersonalized medicine approachPI3K/AktSuccessful clinical interventionNeutrophilic dermatosisFrontline therapyRefractory casesNeutrophilic infiltrateBlood countIL-1βNeutrophil functionNeutrophil migrationTherapeutic responseLiver enzymesClinical challengeIL-1
2022
Reducing the carbon footprint of travel to an international dermatology conference: a case study of the Medical Dermatology Society's Carbon Footprint Program
Belzer A, Rosenbach M, Parker E, Barbieri J, Nelson C. Reducing the carbon footprint of travel to an international dermatology conference: a case study of the Medical Dermatology Society's Carbon Footprint Program. International Journal Of Dermatology 2022, 62: e377-e379. PMID: 36371718, DOI: 10.1111/ijd.16497.Peer-Reviewed Original Research
2020
Geographic disparities in access to scalp cooling for the prevention of chemotherapy-induced alopecia in the United States
Singer S, Tkachenko E, Sharma P, Nelson C, Mostaghimi A, LeBoeuf NR. Geographic disparities in access to scalp cooling for the prevention of chemotherapy-induced alopecia in the United States. Journal Of The American Academy Of Dermatology 2020, 85: 1248-1252. PMID: 32610170, DOI: 10.1016/j.jaad.2020.06.073.Peer-Reviewed Original ResearchA detailed analysis of the distribution, morphology, and histopathology of complex purpura in hospitalized patients: A case series of 68 patients
Gehlhausen JR, Wetter DA, Nelson C, Ramachandran S, McNiff JM, Ko CJ. A detailed analysis of the distribution, morphology, and histopathology of complex purpura in hospitalized patients: A case series of 68 patients. Journal Of The American Academy Of Dermatology 2020, 84: 1188-1196. PMID: 32376433, DOI: 10.1016/j.jaad.2020.04.149.Peer-Reviewed Original ResearchConceptsSmall vessel vasculitisLeukocytoclastic vasculitisMicrovascular occlusionIgA vasculitisCase seriesCommon diagnosisSystemic diseaseDermatologic consultationHigh mortalityTertiary care centerMajority of patientsMedium vessel vasculitisBiopsy findingsHospitalized patientsCare centerRetrospective natureVasculitisDifferential diagnosisInpatient consultationsPurpuraClinical morphologyDiagnostic utilityPatientsInpatientsSuperficial vesselsPatient Perspectives on the Use of Artificial Intelligence for Skin Cancer Screening
Nelson CA, Pérez-Chada LM, Creadore A, Li SJ, Lo K, Manjaly P, Pournamdari AB, Tkachenko E, Barbieri JS, Ko JM, Menon AV, Hartman RI, Mostaghimi A. Patient Perspectives on the Use of Artificial Intelligence for Skin Cancer Screening. JAMA Dermatology 2020, 156: 501-512. PMID: 32159733, PMCID: PMC7066525, DOI: 10.1001/jamadermatol.2019.5014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedArtificial IntelligenceBiopsyEarly Detection of CancerFemaleGrounded TheoryHealth Services AccessibilityHumansInterviews as TopicMaleMass ScreeningMelanomaMiddle AgedObserver VariationPatient Acceptance of Health CarePhysician-Patient RelationsQualitative ResearchReproducibility of ResultsSkin NeoplasmsConceptsSkin cancer screeningCancer screeningSkin cancerPatient's perspectiveAccurate diagnosisDana-Farber Cancer InstituteGeneral dermatology clinicNonmelanoma skin cancerHistory of melanomaHealth care accessPhysician-patient relationshipMelanoma clinicDermatology clinicWomen's HospitalPatient anxietySkin lesionsMAIN OUTCOMECare accessCancer InstitutePatientsQualitative studyCancerHealth careClinicHospitalTeledermatology in the era of COVID-19: Experience of an academic department of dermatology
Perkins S, Cohen JM, Nelson CA, Bunick CG. Teledermatology in the era of COVID-19: Experience of an academic department of dermatology. Journal Of The American Academy Of Dermatology 2020, 83: e43-e44. PMID: 32305442, PMCID: PMC7162755, DOI: 10.1016/j.jaad.2020.04.048.Peer-Reviewed Original ResearchA Multicenter Cross-Sectional Study and Systematic Review of Necrobiotic Xanthogranuloma With Proposed Diagnostic Criteria
Nelson CA, Zhong CS, Hashemi DA, Ashchyan HJ, Brown-Joel Z, Noe MH, Imadojemu S, Micheletti RG, Vleugels RA, Wanat KA, Rosenbach M, Mostaghimi A. A Multicenter Cross-Sectional Study and Systematic Review of Necrobiotic Xanthogranuloma With Proposed Diagnostic Criteria. JAMA Dermatology 2020, 156: 270-279. PMID: 31940000, PMCID: PMC6990734, DOI: 10.1001/jamadermatol.2019.4221.Peer-Reviewed Original ResearchConceptsMulticenter cross-sectional studyNecrobiotic xanthogranulomaCross-sectional studyPlasma cell dyscrasiaDiagnostic criteriaMulticenter cohortMalignant conditionsConsensus exerciseSystematic reviewPeriorbital distributionLymphoproliferative disordersCutaneous lesionsMultiple myelomaMinor criteriaBetter treatment response rateDiagnosis of NXGTertiary academic referral centerNon-Langerhans cell histiocytosisAcademic referral centerTreatment response ratesPennsylvania Health SystemMassachusetts General HospitalBoard-certified dermatologistsIntralesional triamcinoloneIntravenous immunoglobulinBullous pemphigoid after anti–programmed death-1 therapy: A retrospective case-control study evaluating impact on tumor response and survival outcomes
Nelson CA, Singer S, Chen T, Puleo AE, Lian CG, Wei EX, Giobbie-Hurder A, Mostaghimi A, LeBoeuf NR. Bullous pemphigoid after anti–programmed death-1 therapy: A retrospective case-control study evaluating impact on tumor response and survival outcomes. Journal Of The American Academy Of Dermatology 2020, 87: 1400-1402. PMID: 31931083, DOI: 10.1016/j.jaad.2019.12.068.Peer-Reviewed Original Research
2019
Clinical Features and Comorbidities of Patients With Necrobiosis Lipoidica With or Without Diabetes
Hashemi DA, Brown-Joel ZO, Tkachenko E, Nelson CA, Noe MH, Imadojemu S, Vleugels RA, Mostaghimi A, Wanat KA, Rosenbach M. Clinical Features and Comorbidities of Patients With Necrobiosis Lipoidica With or Without Diabetes. JAMA Dermatology 2019, 155: 455-459. PMID: 30785603, PMCID: PMC6523472, DOI: 10.1001/jamadermatol.2018.5635.Peer-Reviewed Original ResearchConceptsNecrobiosis lipoidicaClinical featuresThyroid diseaseDiagnosis of NLRare granulomatous conditionComorbidities of patientsMulticenter retrospective reviewElevated blood glucosePennsylvania Health SystemMassachusetts General HospitalNL lesionsNotable comorbiditiesMedical comorbiditiesMedian hemoglobinPatient demographicsMedian ageRetrospective reviewEpidemiologic characteristicsPathophysiologic characteristicsBiopsy statusGranulomatous conditionsCase reportFemale sexBlood glucoseRisk factors
2018
Human‐computer symbiosis: enhancing dermatologic care while preserving the art of healing
Nelson CA, Kovarik CL, Barbieri JS. Human‐computer symbiosis: enhancing dermatologic care while preserving the art of healing. International Journal Of Dermatology 2018, 57: 1015-1016. PMID: 29873395, DOI: 10.1111/ijd.14071.Peer-Reviewed Original ResearchNeutrophilic dermatoses Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease
Nelson CA, Stephen S, Ashchyan HJ, James WD, Micheletti RG, Rosenbach M. Neutrophilic dermatoses Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease. Journal Of The American Academy Of Dermatology 2018, 79: 987-1006. PMID: 29653210, DOI: 10.1016/j.jaad.2017.11.064.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Cortex HormonesAntineoplastic AgentsAutoimmune DiseasesBehcet SyndromeChemotaxis, LeukocyteCytokinesDermisDiagnosis, DifferentialDrug EruptionsEpidermisEthnicityGenetic Predisposition to DiseaseHidradenitisHumansImmunity, InnateImmunosuppressive AgentsInflammationNeoplasmsNeutrophilsSweet SyndromeVasculitisConceptsNeutrophilic eccrine hidradenitisNeutrophilic dermatosisSweet's syndromeBehçet's diseaseInflammatory skin disorderSignificant patient morbidityUnique clinical featuresMedical education seriesSystemic corticosteroidsBiologic agentsClinical featuresNeutrophilic infiltrateCutaneous lesionsHistopathologic featuresPatient morbidityTherapeutic modalitiesNeoplastic processSkin disordersDermatosesHeterogeneous groupDiseaseDiagnosisHidradenitisDisordersSyndromeNeutrophilic dermatoses Pyoderma gangrenosum and other bowel- and arthritis-associated neutrophilic dermatoses
Ashchyan HJ, Nelson CA, Stephen S, James WD, Micheletti RG, Rosenbach M. Neutrophilic dermatoses Pyoderma gangrenosum and other bowel- and arthritis-associated neutrophilic dermatoses. Journal Of The American Academy Of Dermatology 2018, 79: 1009-1022. PMID: 29653213, DOI: 10.1016/j.jaad.2017.11.063.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Inflammatory AgentsArthritisArthritis, RheumatoidDiagnosis, DifferentialDigestive System Surgical ProceduresDisease ManagementHumansImmunosuppressive AgentsInflammationInflammatory Bowel DiseasesNeutrophilsPostoperative ComplicationsPyoderma GangrenosumReoperationSkin UlcerStill's Disease, Adult-OnsetWound HealingConceptsNeutrophilic dermatosisBowel-associated dermatosis-arthritis syndromeDermatosis-arthritis syndromeRheumatoid neutrophilic dermatitisInflammatory skin disorderSignificant patient morbidityUnique clinical featuresMedical education seriesNeutrophilic dermatitisSystemic corticosteroidsPyoderma gangrenosumClinical characteristicsBiologic agentsClinical featuresNeutrophilic infiltrateCutaneous lesionsHistopathologic featuresPatient morbidityTherapeutic modalitiesNeoplastic processSkin disordersDermatosesHeterogeneous groupDiagnosisGangrenosumThe Association of Age With Clinical Presentation and Comorbidities of Pyoderma Gangrenosum
Ashchyan HJ, Butler DC, Nelson CA, Noe MH, Tsiaras WG, Lockwood SJ, James WD, Micheletti RG, Rosenbach M, Mostaghimi A. The Association of Age With Clinical Presentation and Comorbidities of Pyoderma Gangrenosum. JAMA Dermatology 2018, 154: 409-413. PMID: 29450453, PMCID: PMC5876860, DOI: 10.1001/jamadermatol.2017.5978.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseHematologic malignant neoplasmsMedical comorbiditiesMalignant neoplasmsAssociation of agePyoderma gangrenosumClinical presentationBowel diseaseHematologic disordersMulticenter retrospective cohort studyTertiary academic referral centerInflammatory neutrophilic dermatosisPatients 65 yearsRetrospective cohort studyAcademic referral centerAge-specific evaluationPennsylvania Health SystemMassachusetts General HospitalLarge population studiesDifferent age groupsNeutrophilic dermatosisCohort studyInflammatory arthritisPatient demographicsReferral center
2017
Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center
Nelson CA, Noe MH, McMahon CM, Gowda A, Wu B, Ashchyan HJ, Perl AE, James WD, Micheletti RG, Rosenbach M. Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center. Journal Of The American Academy Of Dermatology 2017, 78: 303-309.e4. PMID: 29107342, DOI: 10.1016/j.jaad.2017.09.013.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdrenal Cortex HormonesAdultAgedAnemiaArthralgiaColchicineDapsoneFemaleFilgrastimFms-Like Tyrosine Kinase 3Folic Acid AntagonistsHematologic AgentsHumansInflammationLeukemia, Myeloid, AcuteLeukopeniaMaleMiddle AgedMutationNeoplasmsNuclear ProteinsNucleophosminPotassium IodideRetrospective StudiesSweet SyndromeTertiary Care CentersThrombocytopeniaTubulin ModulatorsConceptsTertiary academic referral centerAbsence of arthralgiaDrug-induced formsSweet's syndromeAcademic referral centerReferral centerSingle tertiary academic referral centerSetting of malignancyAcute myeloid leukemiaConcurrent malignancyNeutrophilic dermatosisClinicopathologic characteristicsCommon medicationsCommon malignancyRetrospective studyMyeloid leukemiaRetrospective analysisRare disorderPatientsMalignancySyndromePotential associationArthralgiaLeukopeniaThrombocytopenia
2015
Impact of store-and-forward (SAF) teledermatology on outpatient dermatologic care: A prospective study in an underserved urban primary care setting
Nelson CA, Takeshita J, Wanat KA, Bream KD, Holmes JH, Koenig HC, Roth RR, Vuppalapati A, James WD, Kovarik CL. Impact of store-and-forward (SAF) teledermatology on outpatient dermatologic care: A prospective study in an underserved urban primary care setting. Journal Of The American Academy Of Dermatology 2015, 74: 484-490.e1. PMID: 26679528, DOI: 10.1016/j.jaad.2015.09.058.Peer-Reviewed Original ResearchTeledermatology as pedagogy: Diagnostic and management concordance between resident and attending dermatologists
Nelson CA, Wanat KA, Roth RR, James WD, Kovarik CL, Takeshita J. Teledermatology as pedagogy: Diagnostic and management concordance between resident and attending dermatologists. Journal Of The American Academy Of Dermatology 2015, 72: 555-557. PMID: 25687312, PMCID: PMC4373645, DOI: 10.1016/j.jaad.2014.11.011.Peer-Reviewed Original Research
2014
Tele-leprology: a literature review of applications of telemedicine and tele-education to leprosy.
Nelson CA, Kovarik CL, Morssink CB. Tele-leprology: a literature review of applications of telemedicine and tele-education to leprosy. Leprosy Review 2014, 85: 250-61. PMID: 25675649, DOI: 10.47276/lr.85.4.250.Peer-Reviewed Original ResearchThe Reliability of Teledermatology to Triage Inpatient Dermatology Consultations
Barbieri JS, Nelson CA, James WD, Margolis DJ, Littman-Quinn R, Kovarik CL, Rosenbach M. The Reliability of Teledermatology to Triage Inpatient Dermatology Consultations. JAMA Dermatology 2014, 150: 419-424. PMID: 24522374, DOI: 10.1001/jamadermatol.2013.9517.Peer-Reviewed Original Research