2023
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part II diagnosis and management
Wei B, Fox L, Kaffenberger B, Korman A, Micheletti R, Mostaghimi A, Noe M, Rosenbach M, Shinkai K, Kwah J, Phillips E, Bolognia J, Damsky W, Nelson C. Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part II diagnosis and management. Journal Of The American Academy Of Dermatology 2023, 90: 911-926. PMID: 37516356, DOI: 10.1016/j.jaad.2023.02.073.Peer-Reviewed Original ResearchSevere cutaneous adverse reactionsCutaneous adverse reactionsSystemic symptomsDrug reactionsAdverse reactionsDifferential diagnosisDrug-induced hypersensitivity syndrome/drug reactionDrug-induced hypersensitivity syndromeDiHS/DRESSVisceral organ involvementSteroid-sparing agentCornerstone of managementFirst-line therapyEvidence-based overviewSystemic corticosteroidsHypersensitivity syndromeImmediate discontinuationOrgan involvementRisk stratificationAutoimmune diseasesAdjunctive testNeoplastic disordersDiagnostic criteriaLongitudinal evaluationDiagnosis
2020
A detailed analysis of the distribution, morphology, and histopathology of complex purpura in hospitalized patients: A case series of 68 patients
Gehlhausen JR, Wetter DA, Nelson C, Ramachandran S, McNiff JM, Ko CJ. A detailed analysis of the distribution, morphology, and histopathology of complex purpura in hospitalized patients: A case series of 68 patients. Journal Of The American Academy Of Dermatology 2020, 84: 1188-1196. PMID: 32376433, DOI: 10.1016/j.jaad.2020.04.149.Peer-Reviewed Original ResearchConceptsSmall vessel vasculitisLeukocytoclastic vasculitisMicrovascular occlusionIgA vasculitisCase seriesCommon diagnosisSystemic diseaseDermatologic consultationHigh mortalityTertiary care centerMajority of patientsMedium vessel vasculitisBiopsy findingsHospitalized patientsCare centerRetrospective natureVasculitisDifferential diagnosisInpatient consultationsPurpuraClinical morphologyDiagnostic utilityPatientsInpatientsSuperficial vessels