2023
The use of evidence-based medical therapy in patients with critical limb-threatening ischaemia.
Bager L, Petersen J, Havers-Borgersen E, Resch T, Smolderen K, Mena-Hurtado C, Eiberg J, Køber L, Fosbøl E. The use of evidence-based medical therapy in patients with critical limb-threatening ischaemia. European Journal Of Preventive Cardiology 2023, 30: 1092-1100. PMID: 36708037, DOI: 10.1093/eurjpc/zwad022.Peer-Reviewed Original ResearchConceptsEvidence-based medical therapyARB/ACEILimb-threatening ischaemiaMyocardial infarctionMedical therapyHistory of MIHigh-risk patientsFirst-time hospitalizationUnadjusted odds ratioYears of ageMore comorbiditiesPatients 40Hazard ratioDanish registriesOverall mortalityAdjusted analysisAdverse prognosisOdds ratioPractice patternsPatientsMortality rateACEIIschaemiaTherapyMortality
2022
Derivation and validation of a predictive model for chronic stress in patients with cardiovascular disease
Malik AO, Jones PG, Mena-Hurtado C, Burg MM, Shishehbor MH, Hejjaji V, Tran A, Spertus JA, Smolderen KG. Derivation and validation of a predictive model for chronic stress in patients with cardiovascular disease. PLOS ONE 2022, 17: e0275729. PMID: 36256655, PMCID: PMC9578618, DOI: 10.1371/journal.pone.0275729.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesCohort StudiesFemaleHumansMaleMiddle AgedMyocardial InfarctionPeripheral Arterial DiseaseRegistriesRisk FactorsConceptsPeripheral artery diseaseCardiovascular diseaseChronic stressWorse outcomesSymptomatic peripheral artery diseaseMyocardial Infarction RegistryLogistic regression modelsPAD patientsProspective registryCurrent smokingArtery diseaseClinical factorsDerivation cohortValidation cohortC-statisticFemale sexPerceived Stress ScalePatientsEconomic burdenMedical careInstrument scoresSocioeconomic statusPotential targetDiseasePSS-4 scores
2021
Peripheral Artery Disease and COVID-19 Outcomes: Insights from the Yale DOM-CovX Registry
Smolderen KG, Lee M, Arora T, Simonov M, Mena-Hurtado C. Peripheral Artery Disease and COVID-19 Outcomes: Insights from the Yale DOM-CovX Registry. Current Problems In Cardiology 2021, 47: 101007. PMID: 34627824, PMCID: PMC8496926, DOI: 10.1016/j.cpcardiol.2021.101007.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCOVID-19FemaleHumansMaleMiddle AgedMyocardial InfarctionPeripheral Arterial DiseaseRegistriesRisk FactorsSARS-CoV-2StrokeConceptsPeripheral arterial diseaseSARS-CoV-2Myocardial infarctionMajor adverse cardiovascular eventsAdverse cardiovascular eventsPeripheral artery diseaseOdds of mortalityCOVID-19 infectionCOVID-19 outcomesLogistic regression modelsCardiovascular eventsArtery diseaseArterial diseaseMean ageRisk factorsWorse outcomesPatientsMinority raceMortalityRegistryStrokeDiseaseMACERegression modelsOutcomes
2013
An evidence‐based review of the impact of periprocedural myocardial infarction in carotid revascularization
Stilp E, Baird C, Gray WA, Schneider PA, Simonton CA, Verta P, Mena‐Hurtado C. An evidence‐based review of the impact of periprocedural myocardial infarction in carotid revascularization. Catheterization And Cardiovascular Interventions 2013, 82: 709-714. PMID: 23765902, DOI: 10.1002/ccd.25056.Peer-Reviewed Original ResearchConceptsPeriprocedural myocardial infarctionCarotid endarterectomyRevascularization strategyCarotid revascularizationMyocardial infarctionCarotid arteryIncidence of PMIAsymptomatic atherosclerotic stenosisCarotid revascularization strategiesPatient symptom statusLong-term morbidityCarotid artery stenosisExtracranial carotid arteriesEvidence-based reviewAsymptomatic patientsRevascularization TrialLandmark trialsMedical therapyArtery stenosisRandomized comparisonAtherosclerotic stenosisSymptom statusInvasive optionBiomarker assessmentRevascularizationCarotid Revascularization: A Systematic Review of the Evidence
AL‐DAMLUJI M, NAGPAL S, STILP E, REMETZ M, MENA C. Carotid Revascularization: A Systematic Review of the Evidence. Journal Of Interventional Cardiology 2013, 26: 399-410. PMID: 23844747, DOI: 10.1111/joic.12037.Peer-Reviewed Original ResearchConceptsCarotid artery stentingProspective clinical trialsHigh surgical risk patientsSurgical risk patientsEmbolic protection devicesCarotid endarterectomyClinical trialsRisk patientsMyocardial infarctionIncidence rateSafety of CASEffective stroke prevention strategiesHigh surgical risk candidatesLong-term outcome ratesObjective performance criteriaTrials (RCTs) comparing outcomesHigh surgical riskStroke prevention strategiesEvidence-based reviewPatient selection strategiesLong-term effectivenessArtery stentingPeriprocedural safetySurgical riskComparing outcomes