Featured Publications
Guideline-Directed Medical Therapy and Long-Term Mortality and Amputation Outcomes in Patients Undergoing Peripheral Vascular Interventions
Smolderen K, Romain G, Provance J, Scierka L, Mao J, Goodney P, Henke P, Sedrakyan A, Mena-Hurtado C. Guideline-Directed Medical Therapy and Long-Term Mortality and Amputation Outcomes in Patients Undergoing Peripheral Vascular Interventions. JACC Cardiovascular Interventions 2023, 16: 332-343. PMID: 36792257, PMCID: PMC10359106, DOI: 10.1016/j.jcin.2022.09.022.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmputation, SurgicalAngiotensin-Converting Enzyme InhibitorsHeart FailureHumansMedicareMiddle AgedStroke VolumeTreatment OutcomeUnited StatesConceptsGuideline-directed medical therapyPeripheral vascular interventionsMedical therapyVascular interventionsEnzyme inhibitors/angiotensin receptor blockersVascular Quality Initiative registryAngiotensin receptor blockersLong-term mortalityRisk of amputationRisk of mortalityNational quality registryQuality improvement effortsAmputation outcomesAmputation riskMajor amputationAntiplatelet therapyCause mortalityReceptor blockersMean ageVascular careQuality registryObservational studyMortality riskHigh riskAmputation data
2023
The use of evidence-based medical therapy in patients with critical limb-threatening ischaemia.
Bager L, Petersen J, Havers-Borgersen E, Resch T, Smolderen K, Mena-Hurtado C, Eiberg J, Køber L, Fosbøl E. The use of evidence-based medical therapy in patients with critical limb-threatening ischaemia. European Journal Of Preventive Cardiology 2023, 30: 1092-1100. PMID: 36708037, DOI: 10.1093/eurjpc/zwad022.Peer-Reviewed Original ResearchMeSH KeywordsAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsComorbidityFemaleHumansMaleMyocardial InfarctionPeripheral Arterial DiseaseRetrospective StudiesRisk FactorsTreatment OutcomeConceptsEvidence-based medical therapyARB/ACEILimb-threatening ischaemiaMyocardial infarctionMedical therapyHistory of MIHigh-risk patientsFirst-time hospitalizationUnadjusted odds ratioYears of ageMore comorbiditiesPatients 40Hazard ratioDanish registriesOverall mortalityAdjusted analysisAdverse prognosisOdds ratioPractice patternsPatientsMortality rateACEIIschaemiaTherapyMortality
2021
Lack of Guideline-Directed Medical Therapy in Patients Undergoing Endovascular Procedures for Critical Limb Ischemia
Llanos-Chea F, Jelani QU, Trejo-Paredes C, Curtis JP, Parzynski CS, Huang J, Faridi KF, Turner J, Smolderen KG, Mena-Hurtado C. Lack of Guideline-Directed Medical Therapy in Patients Undergoing Endovascular Procedures for Critical Limb Ischemia. Journal Of The American College Of Cardiology 2021, 77: 1374-1375. PMID: 33706882, DOI: 10.1016/j.jacc.2020.12.063.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsCohort StudiesEndovascular ProceduresFemaleGuideline AdherenceHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIschemiaMaleMiddle AgedPeripheral Arterial DiseasePlatelet Aggregation Inhibitors
2017
Evaluation and Management of Erectile Dysfunction in the Hypertensive Patient
Patel JP, Lee EH, Mena-Hurtado CI, Walker CN. Evaluation and Management of Erectile Dysfunction in the Hypertensive Patient. Current Cardiology Reports 2017, 19: 89. PMID: 28836189, DOI: 10.1007/s11886-017-0889-z.Peer-Reviewed Original ResearchMeSH KeywordsAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsErectile DysfunctionHumansHypertensionMalePhosphodiesterase 5 InhibitorsConceptsErectile dysfunctionHypertensive patientsSexual functionCertain antihypertensive agentsAngiotensin receptor blockersChallenging patient populationFirst-line treatmentDiagnosis of hypertensionCalcium channel blockersTreatment of hypertensionPDE-5 inhibitorsAntihypertensive agentsReviewThe prevalencePatient populationPharmacological treatmentRisk factorsChannel blockersClinical challengeCardiovascular fitnessHypertensionEnzyme inhibitorsPatientsDysfunctionAdverse effectsSexual activity