Association between 82Rb positron emission tomography-derived regional myocardial blood flow, severity of angiographic coronary artery stenosis, and mortality in patients with chest pain
Gallegos C, Paredes C, Hu J, Posada E, Saito Y, Lansky A, Shah S, Liu Y, Smolderen K, Mena-Hurtado C, Sinusas A, Miller E. Association between 82Rb positron emission tomography-derived regional myocardial blood flow, severity of angiographic coronary artery stenosis, and mortality in patients with chest pain. Advances In Radiotherapy & Nuclear Medicine 2024, 2: 3786. DOI: 10.36922/arnm.3786.Peer-Reviewed Original ResearchMyocardial flow reserveGlobal myocardial flow reserveQuantitative coronary angiographyAssociated with increased all-cause mortalityPositron emission tomographyCoronary artery stenosis severityMyocardial blood flowAll-cause mortalityCoronary angiographyChest painStenosis severityAngiographic coronary artery stenosisResting myocardial blood flowAcute chest painBlood flowInvasive coronary angiographyLeft circumflex arteryLeft descending arteryRight coronary arteryCoronary artery stenosisStress testCoronary stenosis severityCardiovascular eventsDescending arteryWeak correlationComparison of mortality and amputation after lower extremity bypass versus peripheral vascular intervention in patients with chronic limb-threatening ischemia and comorbid chronic kidney disease
Cleman J, Sierra J, Romain G, Capuano B, Scierka L, Callegari S, Jacque F, Peri-Okonny P, Nagpal S, Smolderen K, Mena-Hurtado C. Comparison of mortality and amputation after lower extremity bypass versus peripheral vascular intervention in patients with chronic limb-threatening ischemia and comorbid chronic kidney disease. Journal Of Vascular Surgery 2024, 80: 480-489.e5. PMID: 38608966, DOI: 10.1016/j.jvs.2024.04.016.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaAll-cause mortalityLower extremity bypassPeripheral vascular interventionsComorbid chronic kidney diseaseLimb-threatening ischemiaComparison of mortalityPreference-sensitive treatment decisionsCox proportional hazards modelsRisk of deathInteraction termsProportional hazards modelLower-extremity bypassChronic kidney diseaseFine-Gray modelMortality riskVascular interventionsAmputationHazards modelOutcome dataFine-GrayAssociated with worse outcomesHigh riskKidney diseasePropensity score