Exercise modulates the interaction between cognition and anxiety in humans
Lago TR, Hsiung A, Leitner BP, Duckworth CJ, Balderston NL, Chen KY, Grillon C, Ernst M. Exercise modulates the interaction between cognition and anxiety in humans. Cognition & Emotion 2018, 33: 863-870. PMID: 30032703, PMCID: PMC6344312, DOI: 10.1080/02699931.2018.1500445.Peer-Reviewed Original ResearchConceptsAnxiety-potentiated startleAttention controlTask-relevant stimulus processingInterplay of cognitionThreat of shockThreat interferenceThreat processingWM loadWM taskMemory loadWM performanceStimulus processingCognitive abilitiesAnxiolytic effectsAnxiety disordersCognitionAnxietyType of activityProcessingFuture studiesStartleTaskHealthy volunteersParticipantsImpairmentExercise decreases defensive responses to unpredictable, but not predictable, threat
Lago TR, Hsiung A, Leitner BP, Duckworth CJ, Chen KY, Ernst M, Grillon C. Exercise decreases defensive responses to unpredictable, but not predictable, threat. Depression And Anxiety 2018, 35: 868-875. PMID: 29637654, PMCID: PMC6314494, DOI: 10.1002/da.22748.Peer-Reviewed Original ResearchConceptsSessions of exerciseInfluence of exercisePredictable threatSustained responseClinical indicationsHealthy controlsAnxiolytic effectsHealthy volunteersPhasic responseThreat testBehavioral interventionsAnxiety disordersControl activitiesDefensive responsesUnpredictable threatStartle potentiationExercisePotentiationNeurobehavioral mechanismsEyeblink startleResponseUnpredictable shocksProvide cluesDefensive stateThreat responses