Isolated Thrombocytopenia After Allogeneic Bone Marrow Transplantation: Existence of Transient and Chronic Thrombocytopenic Syndromes
First L, Smith B, Lipton J, Nathan D, Parkman R, Rappeport J. Isolated Thrombocytopenia After Allogeneic Bone Marrow Transplantation: Existence of Transient and Chronic Thrombocytopenic Syndromes. Blood 1985, 65: 368-374. DOI: 10.1182/blood.v65.2.368.368.Peer-Reviewed Original ResearchBone marrow transplantationMarrow transplantationThrombocytopenic syndromesChronic GVHDIsolated thrombocytopeniaPlatelet countThrombocytopenic patientsTransient thrombocytopeniaAllogeneic bone marrow transplantationSevere acute graftTrimethoprim-sulfamethoxazole administrationPeripheral platelet destructionTotal body irradiationBone marrow biopsyNormal platelet countAdverse patient prognosisNumber of megakaryocytesAcute graftIneffective thrombopoiesisPretransplant preparationHost diseasePreparatory regimensBody irradiationPlatelet destructionPlatelet precursorsIsolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
First LR, Smith BR, Lipton J, Nathan DG, Parkman R, Rappeport JM. Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes. Blood 1985, 65: 368-74. PMID: 3881142, DOI: 10.1182/blood.v65.2.368.bloodjournal652368.Peer-Reviewed Original ResearchConceptsBone marrow transplantationMarrow transplantationThrombocytopenic syndromesChronic GVHDIsolated thrombocytopeniaPlatelet countThrombocytopenic patientsTransient thrombocytopeniaAllogeneic bone marrow transplantationSevere acute graftTrimethoprim-sulfamethoxazole administrationPeripheral platelet destructionTotal body irradiationBone marrow biopsyNormal platelet countAdverse patient prognosisNumber of megakaryocytesAcute graftIneffective thrombopoiesisPretransplant preparationHost diseasePreparatory regimensBody irradiationPlatelet destructionPlatelet precursors