1994
Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass
Rinder C, Gaal D, Student L, Smith B. Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass. Journal Of Thoracic And Cardiovascular Surgery 1994, 107: 280-288. PMID: 8283897, DOI: 10.1016/s0022-5223(94)70482-1.Peer-Reviewed Original ResearchConceptsCongenital heart diseasePlatelet-leukocyte conjugatesNoncyanotic congenital heart diseaseCardiopulmonary bypassHeart diseasePediatric patientsNoncyanotic patientsLeukocyte activationPlatelet glycoprotein IbNeutrophil-platelet conjugatesPlatelet–leukocyte activationTermination of bypassCyanotic heart diseaseEnd of bypassMonocyte-platelet conjugatesGlycoprotein IbNoncyanotic heart diseaseActivation of plateletsInflammatory complicationsPulmonary dysfunctionCyanotic patientsPlatelet adhesion receptorsCD11b expressionClinical riskBaseline values
1991
Modulation of Platelet Surface Adhesion Receptors during Cardiopulmonary Bypass
Rinder C, Mathew J, Rinder H, Bonan J, Ault K, Smith B. Modulation of Platelet Surface Adhesion Receptors during Cardiopulmonary Bypass. Anesthesiology 1991, 75: 563-570. PMID: 1718190, DOI: 10.1097/00000542-199110000-00004.Peer-Reviewed Original ResearchConceptsIIb/IIIaCardiopulmonary bypassGlycoprotein IIb/IIIaPlatelet activationQualitative platelet defectsGlycoprotein IVGlycoprotein IbAlpha-granule releaseGranule membrane protein-140Surface glycoprotein IbHLA APlatelet functionBaseline valuesVon Willebrand factor receptorBypassThrombospondin receptorGlycoprotein Ib expressionFlow cytometryIb expressionPlatelet defectsSelective decreasePlatelet receptorsFactor receptorReceptorsProtein 140