2015
The Role of Adjuvant Therapy in the Management of Head and Neck Merkel Cell Carcinoma
Chen MM, Roman SA, Sosa JA, Judson BL. The Role of Adjuvant Therapy in the Management of Head and Neck Merkel Cell Carcinoma. JAMA Otolaryngology - Head & Neck Surgery 2015, 141: 137. PMID: 25474617, DOI: 10.1001/jamaoto.2014.3052.Peer-Reviewed Original ResearchConceptsNeck Merkel cell carcinomaMerkel cell carcinomaAdjuvant radiation therapyAdjuvant chemoradiotherapyManagement of headOverall survivalRadiation therapyPositive marginsAdjuvant therapySurgical excisionTumor sizeCell carcinomaMAIN OUTCOMECox proportional hazards regression analysisNational Cancer Data BaseProportional hazards regression analysisKaplan-Meier survival analysisDifferent adjuvant therapiesStandard surgical excisionImproved overall survivalDecreased overall survivalHigh-risk patientsMetastatic lymph nodesHazards regression analysisLarger tumor size
2014
Prognostic factors for squamous cell cancer of the parotid gland: An analysis of 2104 patients
Chen MM, Roman SA, Sosa JA, Judson BL. Prognostic factors for squamous cell cancer of the parotid gland: An analysis of 2104 patients. Head & Neck 2014, 37: 1-7. PMID: 24339135, DOI: 10.1002/hed.23566.Peer-Reviewed Original ResearchConceptsSquamous cell cancerCell cancerRadiation therapyCutaneous squamous cell cancerCommon parotid malignancyAdjuvant radiation therapyDisease-specific mortalityDisease-specific survivalEnd Results (SEER) databaseYears of ageExtraparenchymal extensionCervical metastasisParotid malignanciesAdult patientsPrimary malignancyImproved survivalPrognostic factorsDistant metastasisResults databasePoor prognosisTumor sizeTreatment outcomesParotid glandPatientsSurgery
2013
Histologic grade as prognostic indicator for mucoepidermoid carcinoma: A population‐level analysis of 2400 patients
Chen MM, Roman SA, Sosa JA, Judson BL. Histologic grade as prognostic indicator for mucoepidermoid carcinoma: A population‐level analysis of 2400 patients. Head & Neck 2013, 36: 158-163. PMID: 23765800, DOI: 10.1002/hed.23256.Peer-Reviewed Original ResearchConceptsHigh-grade mucoepidermoid carcinomaDisease-specific survivalMucoepidermoid carcinomaNodal metastasisFive-year DSS ratesIntermediate-grade mucoepidermoid carcinomaEnd Results (SEER) databaseNegative prognostic factorParotid mucoepidermoid carcinomaHigh gradeFirst population-level studyExtraparenchymal extensionDSS ratesPatient ageUncommon malignancyPrognostic factorsDistant metastasisResults databaseTumor sizeHistologic gradePrognostic indicatorLevel IParotid glandMetastasisLarger study