2015
The Role of Adjuvant Therapy in the Management of Head and Neck Merkel Cell Carcinoma
Chen MM, Roman SA, Sosa JA, Judson BL. The Role of Adjuvant Therapy in the Management of Head and Neck Merkel Cell Carcinoma. JAMA Otolaryngology - Head & Neck Surgery 2015, 141: 137. PMID: 25474617, DOI: 10.1001/jamaoto.2014.3052.Peer-Reviewed Original ResearchConceptsNeck Merkel cell carcinomaMerkel cell carcinomaAdjuvant radiation therapyAdjuvant chemoradiotherapyManagement of headOverall survivalRadiation therapyPositive marginsAdjuvant therapySurgical excisionTumor sizeCell carcinomaMAIN OUTCOMECox proportional hazards regression analysisNational Cancer Data BaseProportional hazards regression analysisKaplan-Meier survival analysisDifferent adjuvant therapiesStandard surgical excisionImproved overall survivalDecreased overall survivalHigh-risk patientsMetastatic lymph nodesHazards regression analysisLarger tumor size
2014
Predictors of survival in carcinoma ex pleomorphic adenoma
Chen MM, Roman SA, Sosa JA, Judson BL. Predictors of survival in carcinoma ex pleomorphic adenoma. Head & Neck 2014, 36: 1324-1328. PMID: 23956034, DOI: 10.1002/hed.23453.Peer-Reviewed Original ResearchConceptsDisease-specific survivalCervical lymph node metastasisLymph node metastasisCa ex-PAPleomorphic adenomaLymph nodesNode metastasisMultiple cervical lymph node metastasesMultiple metastatic lymph nodesPositive lymph nodesEnd Results (SEER) databaseMetastatic lymph nodesPredictors of survivalHigh-grade carcinomaCarcinoma ex pleomorphic adenomaEx pleomorphic adenomaFirst population-level analysisBenign pleomorphic adenomaExtraparenchymal extensionCervical metastasisIndependent predictorsDistant metastasisPrognostic featuresResults databasePoor prognosis