1983
Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—2. Action potential generating mechanisms and morphological correlates
Grace A, Bunney B. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—2. Action potential generating mechanisms and morphological correlates. Neuroscience 1983, 10: 317-331. PMID: 6633864, DOI: 10.1016/0306-4522(83)90136-7.Peer-Reviewed Original ResearchConceptsInitial segment spikesDopamine neuronsSlow depolarizationAction potentialsAxon hillockDendritic dopamine releaseLong-duration afterhyperpolarizationNigral dopamine neuronsLow-threshold spikesLucifer yellow injectionExtracellular recording techniquesLong-duration spikesAction potential generationDopaminergic neuronsSpecific ionic currentsIntracellular recordingsDopamine releaseIntracellular injectionElectrophysiological studiesDendritic spikesMajor dendritesNeuron 2Action potential generating mechanismSomatic regionNeuronal compartments
1981
Peptide-monoamine coexistence: Studies of the actions of cholecystokinin-like peptide on the electrical activity of midbrain dopamine neurons
Skirboll L, Grace A, Hommer D, Rehfeld J, Goldstein M, Hökfelt T, Bunney B. Peptide-monoamine coexistence: Studies of the actions of cholecystokinin-like peptide on the electrical activity of midbrain dopamine neurons. Neuroscience 1981, 6: 2111-2124. PMID: 6120481, DOI: 10.1016/0306-4522(81)90002-6.Peer-Reviewed Original ResearchConceptsCholecystokinin-like peptidesVentral tegmental areaDopaminergic neuronsFiring rateSubstantia nigraTegmental areaDopaminergic cellsExtracellular single-unit recording techniquesMidbrain dopamine-containing neuronsSingle-unit recording techniquesDopamine-containing neuronsBrain dopaminergic systemDopamine-rich areasMidbrain dopamine neuronsDepolarization inactivationResponsive neuronsDopamine neuronsDopaminergic systemComparable dosesTyrosine hydroxylaseCholecystokininBursting activityNeuronsImmunocytochemical techniquesRecording techniques