1989
Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin
Sesack S, Deutch A, Roth R, Bunney B. Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin. The Journal Of Comparative Neurology 1989, 290: 213-242. PMID: 2592611, DOI: 10.1002/cne.902900205.Peer-Reviewed Original ResearchConceptsEfferent projectionsPhaseolus vulgaris leucoagglutininTopographical organizationInjection sitePrelimbic areaAnterograde tract‐tracing studyBasal forebrain nucleiAnterior olfactory nucleusLaterodorsal tegmental nucleusMesencephalic trigeminal nucleusIntralaminar thalamic nucleiMedullary reticular formationTract-tracing studiesDeep mesencephalic nucleusPeriaqueductal gray regionCytoarchitectonic divisionsCentral gray areaMedial prefrontal cortexVentral midbrain tegmentumOlfactory nucleusRaphe nucleusPrelimbic divisionLateral hypothalamusMesencephalic nucleusTrigeminal nucleus
1975
Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine
Svensson T, Bunney B, Aghajanian G. Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine. Brain Research 1975, 92: 291-306. PMID: 1174954, DOI: 10.1016/0006-8993(75)90276-0.Peer-Reviewed Original ResearchConceptsNE neuronsAgonist clonidineHigh dosesMidbrain dorsal raphe nucleusAlpha-adrenergic agonist clonidineSingle-unit recording techniquesBrain NE neuronsClonidine-induced depressionDorsal raphe nucleusAdrenergic agonist clonidineBrain norepinephrineRaphe neuronsIntravenous clonidineAdrenergic transmissionSerotonergic neuronsDepressant effectDopaminergic neuronsRaphe nucleusSpontaneous firingLocus coeruleusClonidineLow doseL-amphetamineAdrenergic receptorsNeurons
1974
Noradrenergic neurons: Morphine inhibition of spontaneous activity
Korf J, Bunney B, Aghajanian G. Noradrenergic neurons: Morphine inhibition of spontaneous activity. European Journal Of Pharmacology 1974, 25: 165-169. PMID: 4435020, DOI: 10.1016/0014-2999(74)90045-4.Peer-Reviewed Original ResearchConceptsLocus coeruleusMorphine sulfateFiring rateNeuronal activitySpontaneous activityNoradrenergic neuron activityNorepinephrine-containing neuronsNoradrenergic neuronal activityLocus coeruleus cellsSpontaneous firing rateDorsal raphe nucleusAnalgesic actionMorphine inhibitionSerotonergic neuronsRaphe nucleusMorphine antagonistNoxious stimuliNE cellsNeuron activityCoeruleusMorphineNeuronsNaloxoneInhibitionCells