Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells
Williamson AJ, Jacobson R, van Praagh JB, Gaines S, Koo HY, Lee B, Chan WC, Weichselbaum R, Alverdy JC, Zaborina O, Shogan BD. Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells. Neoplasia 2022, 27: 100787. PMID: 35366466, PMCID: PMC8971311, DOI: 10.1016/j.neo.2022.100787.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCollagenasesColonic NeoplasmsEnterococcus faecalisHumansMicePhenotypeUrokinase-Type Plasminogen ActivatorConceptsE. faecalisTumor progressionCollagenolytic bacteriaPost-surgical recoveryHuman colon cancer specimensMurine colon cancer cell lineEnterococcus faecalisColon cancer developmentColon cancer specimensColon cancer cell linesCancer cell invasionCurative resectionCancer cell linesColon cancer cellsCancer specimensMouse modelIntestinal microbesCT26 cellsCancer developmentTumor developmentCollagenase productionTumor formationCancer cellsInvasive phenotypeCell invasion