2020
Staphylococcus aureus α-toxin suppresses antigen-specific T cell responses
Lee B, Olaniyi R, Kwiecinski JM, Wardenburg JB. Staphylococcus aureus α-toxin suppresses antigen-specific T cell responses. Journal Of Clinical Investigation 2020, 130: 1122-1127. PMID: 31873074, PMCID: PMC7269593, DOI: 10.1172/jci130728.Peer-Reviewed Original ResearchConceptsT cell responsesSkin infectionsCell responsesAntigen-specific T cell responsesOVA-specific T cell responsesT cell-mediated immunityS. aureusΑ-toxinAntigen-specific modelChicken egg OVACell-mediated immunityT cell memoryAntigen-specific memoryPrimary skin infectionsInvasive staphylococcal diseaseStaphylococcus aureus α-toxinDevelopment of immunityΑ-toxin expressionAureus α-toxinProtective immunityInvasive infectionsLeading causeLoss of DCsStaphylococcal diseaseLong-term protection
2018
A common approach to toxin specificity
Lee B, Bubeck Wardenburg J. A common approach to toxin specificity. Nature Microbiology 2018, 3: 644-645. PMID: 29795538, DOI: 10.1038/s41564-018-0173-z.Peer-Reviewed Original Research