2024
Automated vessel-specific coronary artery calcification quantification with deep learning in a large multi-centre registry
Williams M, Shanbhag A, Zhou J, Michalowska A, Lemley M, Miller R, Killekar A, Waechter P, Gransar H, Van Kriekinge S, Builoff V, Feher A, Miller E, Bateman T, Dey D, Berman D, Slomka P. Automated vessel-specific coronary artery calcification quantification with deep learning in a large multi-centre registry. European Heart Journal - Cardiovascular Imaging 2024, 25: 976-985. PMID: 38376471, PMCID: PMC11210989, DOI: 10.1093/ehjci/jeae045.Peer-Reviewed Original ResearchCoronary artery calcificationRight coronary arteryAttenuation correction CTGated CTAgatston unitsLeft circumflexHazard ratioCoronary artery calcification quantificationMulti-center registryAdverse cardiovascular eventsYear follow-upConfidence intervalsLinear weighted Cohen's kappaPrognostic implicationsMulticenter registryPrognostic assessmentCardiovascular eventsArtery calcificationCoronary arteryAttenuation correctionCohen's kappaLM/LADRegistry
2023
Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging
Feher A, Pieszko K, Shanbhag A, Lemley M, Miller R, Huang C, Miras L, Liu Y, Gerber J, Sinusas A, Miller E, Slomka P. Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging. The International Journal Of Cardiovascular Imaging 2023, 40: 185-193. PMID: 37845406, PMCID: PMC466934, DOI: 10.1007/s10554-023-02980-1.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsCoronary artery calcificationMyocardial perfusion imagingCT myocardial perfusion imagingSPECT/CT myocardial perfusion imagingArtery calcificationPrognostic valuePrior coronary stentingAdverse cardiovascular eventsSimilar prognostic valueSPECT myocardial perfusionREFINE SPECT registrySPECT/CTCardiovascular eventsCAC scoringCalcium scoreCoronary calcificationCoronary stentingPrognostic utilitySingle centerCoronary arteryLow doseMyocardial perfusionPerfusion imagingSurvival analysis
2022
Novel Cardiac Computed Tomography Methods for the Assessment of Anthracycline Induced Cardiotoxicity
Feher A, Baldassarre LA, Sinusas AJ. Novel Cardiac Computed Tomography Methods for the Assessment of Anthracycline Induced Cardiotoxicity. Frontiers In Cardiovascular Medicine 2022, 9: 875150. PMID: 35571206, PMCID: PMC9094702, DOI: 10.3389/fcvm.2022.875150.Peer-Reviewed Original ResearchCardiac structureEpicardial coronary arteriesAnthracycline-induced cardiotoxicityAnti-cancer therapyCoronary vasoreactivityCoronary anatomyCoronary arteryInduced cardiotoxicityCardiac functionCardiotoxic effectsPreprocedural planningExtracellular volumeMyocardial deformationPotential roleCardiotoxicityMolecular imagingCurrent manuscriptVasoreactivityComputed tomography methodArteryAnthracyclinesTherapyCardiacPlaquesEvaluation
2017
Quantitative Assessment of Coronary Microvascular Function
Feher A, Sinusas AJ. Quantitative Assessment of Coronary Microvascular Function. Circulation Cardiovascular Imaging 2017, 10: e006427. PMID: 28794138, PMCID: PMC5678979, DOI: 10.1161/circimaging.117.006427.Peer-Reviewed Original ResearchMeSH KeywordsComputed Tomography AngiographyCoronary AngiographyCoronary CirculationEchocardiographyHeart DiseasesHumansMagnetic Resonance ImagingMicrocirculationMyocardial Perfusion ImagingPositron-Emission TomographyPredictive Value of TestsPrognosisReproducibility of ResultsTomography, Emission-Computed, Single-PhotonConceptsCoronary microvascular dysfunctionMyocardial blood flowMicrovascular dysfunctionBlood flowMyocardial perfusionCoronary microvascular impairmentCoronary microvascular functionEpicardial coronary arteriesNormal myocardial perfusionMyocardial contrast echocardiographyAbsolute myocardial blood flowImportant prognostic relevanceMagnetic resonance imagingPositron emission tomographySingle photon emissionMicrovascular impairmentMicrovascular functionMultiple imaging modalitiesPrognostic relevanceCoronary arteryCoronary flowCoronary perfusionContrast echocardiographyClinical valueFunctional microcirculation