2001
Left ventricular midwall function improves with antihypertensive therapy and regression of left ventricular hypertrophy in patients with asymptomatic hypertension
Schussheim A, Diamond J, Phillips R. Left ventricular midwall function improves with antihypertensive therapy and regression of left ventricular hypertrophy in patients with asymptomatic hypertension. The American Journal Of Cardiology 2001, 87: 61-65. PMID: 11137835, DOI: 10.1016/s0002-9149(00)01273-x.Peer-Reviewed Original ResearchConceptsMidwall fractional shorteningLV mass regressionAntihypertensive therapyAsymptomatic hypertensionVentricular hypertrophyMidwall functionMass regressionEarly hypertensive heart diseaseConventional echocardiographic parametersHypertensive heart diseaseLeft ventricular massPotential beneficial effectsEchocardiographic parametersFractional shorteningHypertensive personsIndependent predictorsVentricular massDrug therapyMyocardial performanceHeart diseaseCardiac performanceVentricular geometryChamber functionPatientsTherapy
1998
Midwall fractional shortening is an independent predictor of left ventricular diastolic dysfunction in asymptomatic patients with systemic hypertension
Schussheim A, Diamond J, Jhang J, Phillips R. Midwall fractional shortening is an independent predictor of left ventricular diastolic dysfunction in asymptomatic patients with systemic hypertension. The American Journal Of Cardiology 1998, 82: 1056-1059. PMID: 9817481, DOI: 10.1016/s0002-9149(98)00558-x.Peer-Reviewed Original ResearchConceptsMidwall fractional shorteningAbnormal diastolic functionMidwall shorteningHypertensive patientsSystolic functionDiastolic functionFractional shorteningDiastolic dysfunctionBlood pressureIndependent predictorsSystolic performanceEndocardial shorteningFiber shorteningLeft ventricular systolic performanceDepressed midwall shorteningHealthy hypertensive patientsLV diastolic abnormalitiesLV inflow velocityNormal midwall shorteningTarget organ damageVentricular diastolic dysfunctionIsovolumic relaxation timeLV systolic functionHigh blood pressureVentricular systolic performanceK001: Depressed midwall fractional shortening predicts diastolic dysfunction in asymptomatic hypertensive patients
Schussheim A, Diamond J, Jhang J, Phillips R. K001: Depressed midwall fractional shortening predicts diastolic dysfunction in asymptomatic hypertensive patients. American Journal Of Hypertension 1998, 11: 183a-183a. DOI: 10.1016/s0895-7061(97)91382-0.Peer-Reviewed Original Research
1997
Usefulness of Subnormal Midwall Fractional Shortening in Predicting Left Ventricular Exercise Dysfunction in Asymptomatic Patients With Systemic Hypertension
Schussheim A, Devereux R, de Simone G, Borer J, Herrold E, Laragh J. Usefulness of Subnormal Midwall Fractional Shortening in Predicting Left Ventricular Exercise Dysfunction in Asymptomatic Patients With Systemic Hypertension. The American Journal Of Cardiology 1997, 79: 1070-1074. PMID: 9114766, DOI: 10.1016/s0002-9149(97)00049-0.Peer-Reviewed Original ResearchConceptsMidwall fractional shorteningAsymptomatic hypertensive patientsLV ejection fractionFractional shorteningBlood pressureHypertensive patientsEjection fractionHigher mean diastolic blood pressureExtracardiac target organ damageHigher urinary protein excretionLower midwall fractional shorteningMean diastolic blood pressureLV functional reserveSerum creatinine levelsTarget organ damageUrinary protein excretionDiastolic blood pressureSystolic blood pressureHigher LV massBody mass indexIdentification of patientsExercise dysfunctionAsymptomatic patientsSystemic hypertensionCreatinine levels