2021
Fecal Microbial Transplant in Individuals With Immune-Mediated Dry Eye
Watane A, Cavuoto K, Rojas M, Dermer H, Day J, Banerjee S, Galor A. Fecal Microbial Transplant in Individuals With Immune-Mediated Dry Eye. American Journal Of Ophthalmology 2021, 233: 90-100. PMID: 34214453, PMCID: PMC8678170, DOI: 10.1016/j.ajo.2021.06.022.Peer-Reviewed Original ResearchConceptsGut microbiome profilesT cell profileFecal microbial transplantDry eyeMicrobiome profilesMicrobial transplantDE symptomsRegulatory T-cell profilesDE symptom severityNonrandomized clinical trialPrimary outcome measureDonor microbiomeSingle healthy donorAdverse eventsMean ageClinical trialsHealthy donorsOutcome measuresStudy populationSymptom severityAdministration methodsBaseline profileGenus FaecalibacteriumTime pointsMonths
2020
Investigating retinal blood flow characteristics and amyloid formation in patients with type 2 diabetes and mild cognitive impairment
DeBuc D, Sapahia R, Watane A, Cho K, Rege A. Investigating retinal blood flow characteristics and amyloid formation in patients with type 2 diabetes and mild cognitive impairment. Alzheimer's & Dementia 2020, 16 DOI: 10.1002/alz.045626.Peer-Reviewed Original ResearchOptic nerve headRetinal blood flowMild cognitive impairmentType 2 diabetesHealthy subjectsCognitive impairmentNerve headBlood flowLimited study populationBackground PatientsBlood pressureArterial stiffnessT2D subjectsBlood flow characteristicsStudy populationKruskal-Wallis testMethods ThirtyMCI subjectsAlzheimer's diseasePatientsPotential biomarkersGreater riskLarger studyRetinal imagerPilot study