Fecal Microbial Transplant in Individuals With Immune-Mediated Dry Eye
Watane A, Cavuoto K, Rojas M, Dermer H, Day J, Banerjee S, Galor A. Fecal Microbial Transplant in Individuals With Immune-Mediated Dry Eye. American Journal Of Ophthalmology 2021, 233: 90-100. PMID: 34214453, PMCID: PMC8678170, DOI: 10.1016/j.ajo.2021.06.022.Peer-Reviewed Original ResearchConceptsGut microbiome profilesT cell profileFecal microbial transplantDry eyeMicrobiome profilesMicrobial transplantDE symptomsRegulatory T-cell profilesDE symptom severityNonrandomized clinical trialPrimary outcome measureDonor microbiomeSingle healthy donorAdverse eventsMean ageClinical trialsHealthy donorsOutcome measuresStudy populationSymptom severityAdministration methodsBaseline profileGenus FaecalibacteriumTime pointsMonths