2024
Sex‐specific analysis in patients undergoing Talar OsteoPeriostic grafting from the Iliac Crest (TOPIC) for large osteochondral lesions of the talus
Dahmen J, Gianakos A, Hollander J, Rikken Q, Stufkens S, Kerkhoffs G. Sex‐specific analysis in patients undergoing Talar OsteoPeriostic grafting from the Iliac Crest (TOPIC) for large osteochondral lesions of the talus. Knee Surgery, Sports Traumatology, Arthroscopy 2024, 32: 2679-2687. PMID: 38796727, DOI: 10.1002/ksa.12257.Peer-Reviewed Original ResearchFoot and Ankle Outcome ScoreNumerical rating scaleTopical proceduresClinical outcomesComputed tomographyIliac crestLesion sizeMonths of follow-upPreoperative lesion sizeClinically relevant improvementAnkle Outcome ScorePain scoresNo significant differenceFemale patientsMale patientsConsecutive femalesSex-specific analysesFollow-upTreatment strategiesGraft consolidationOutcome scoresPrimary outcomeAssess consolidationLesion volumeLevel III
2022
Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role?
Gianakos A, Okedele O, Mulcahey M, Kerkhoffs G, Kennedy J. Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role? The Journal Of Foot & Ankle Surgery 2022, 62: 96-101. PMID: 35753861, DOI: 10.1053/j.jfas.2022.05.005.Peer-Reviewed Original ResearchConceptsAutologous osteochondral transplantationFemale patientsOsteochondral lesionsMale patientsOsteochondral transplantationPotential gender-related differencesCartilage repair tissue (MOCART) scoreMean MOCART scoreAnkle Outcome ScoreMechanism of injuryChronic ankle instabilityTalar osteochondral lesionsGender-related differencesMean FAOSConsecutive patientsMagnetic resonance observationOutcome scoresFunctional outcomeMOCART scoreAnkle instabilityPatientsDemographic dataTissue scoresLesionsRehabilitation strategiesGender Differences May Exist in the Presentation, Mechanism of Injury and Outcomes Following Bone Marrow Stimulation for Osteochondral Lesions of the Talus
Gianakos A, Williamson E, Mercer N, Kerkhoffs G, Kennedy J. Gender Differences May Exist in the Presentation, Mechanism of Injury and Outcomes Following Bone Marrow Stimulation for Osteochondral Lesions of the Talus. The Journal Of Foot & Ankle Surgery 2022, 62: 75-79. PMID: 35659478, DOI: 10.1053/j.jfas.2022.04.010.Peer-Reviewed Original ResearchConceptsBone marrow stimulationMale patientsFemale patientsPain scoresOsteochondral lesionsMarrow stimulationCartilage repair tissue (MOCART) scoreSymptomatic osteochondral lesionsAnkle Outcome ScoreShort Form-12Mechanism of injuryMagnetic resonance observationYears postsurgeryClinical outcomesOutcome scoresSurgical outcomesRetrospective analysisAnkle biomechanicsPatientsMedial lesionsLateral lesionsLesionsTissue scoresCartilage morphologyOutcomesImproved Clinical Outcomes and Patient Satisfaction of In-Office Needle Arthroscopy for the Treatment of Posterior Ankle Impingement
Mercer N, Samsonov A, Dankert J, Gianakos A, Stornebrink T, Delmonte R, Kerkhoffs G, Kennedy J. Improved Clinical Outcomes and Patient Satisfaction of In-Office Needle Arthroscopy for the Treatment of Posterior Ankle Impingement. Arthroscopy Sports Medicine And Rehabilitation 2022, 4: e629-e638. PMID: 35494297, PMCID: PMC9042901, DOI: 10.1016/j.asmr.2021.12.004.Peer-Reviewed Original ResearchPosterior ankle impingement syndromeClinical outcomesPatient satisfactionMedian timeOutcome scoresNeedle arthroscopyOutcomes Measurement Information System (PROMIS) pain interferenceShort-term clinical outcomesExcellent patient-reported outcomesTherapeutic case seriesRetrospective cohort studySignificant pain reductionAnkle impingement syndromePain intensity scoresPostoperative outcome scoresAnkle Outcome ScoreLow complication ratePosterior ankle impingementPatient-reported outcomesSports activitiesImproved clinical outcomesHigh patient satisfactionQuality of lifeOffice needle arthroscopyWilcoxon signed-rank testAutologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes?
Gianakos A, Okedele O, Flynn S, Mulcahey M, Kennedy J. Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes? Foot & Ankle Orthopaedics 2022, 7: 2473011421s00204. PMCID: PMC8795102, DOI: 10.1177/2473011421s00204.Peer-Reviewed Original ResearchAutologous osteochondral transplantationTalar osteochondral lesionsFemale patientsMale patientsChronic ankle instabilityOsteochondral lesionsOsteochondral transplantationAnkle instabilityKnee donor-site morbidityCartilage repair tissue (MOCART) scoreMean MOCART scoreLonger symptom durationAnkle Outcome ScoreDonor site morbidityMean FAOSFAOS scoresSymptom durationComplication rateConsecutive patientsMagnetic resonance observationOutcome scoresFunctional outcomeRevision surgeryMOCART scorePatientsGender May Affect Mid-Term Outcomes Following Bone Marrow Stimulation for Osteochondral Lesions of the Talus
Gianakos A, Williamson E, Kennedy J. Gender May Affect Mid-Term Outcomes Following Bone Marrow Stimulation for Osteochondral Lesions of the Talus. Foot & Ankle Orthopaedics 2022, 7: 2473011421s00205. PMCID: PMC8794953, DOI: 10.1177/2473011421s00205.Peer-Reviewed Original ResearchBone marrow stimulationMale patientsFemale patientsPain scoresMagnetic resonance imagingOsteochondral lesionsLateral lesionsMarrow stimulationMean MOCART scoreSymptomatic osteochondral lesionsMean patient ageMid-term outcomesAnkle Outcome ScoreShort Form-12Treatment of OLTSignificant differencesCartilage repair tissueConcomitant proceduresPatient ageMagnetic resonance observationClinical outcomesOutcome scoresSurgical interventionMOCART scoreTraumatic etiologyClinical Outcomes of Nano Arthroscopy in the Office Setting for the Treatment of Posterior Ankle Impingement
Mercer N, Samsonov A, Dankert J, Delmonte R, Stornebrink T, Gianakos A, Kerkhoffs G, Kennedy J, Dahmen J. Clinical Outcomes of Nano Arthroscopy in the Office Setting for the Treatment of Posterior Ankle Impingement. Foot & Ankle Orthopaedics 2022, 7: 2473011421s00363. PMCID: PMC8793393, DOI: 10.1177/2473011421s00363.Peer-Reviewed Original ResearchBody mass indexPosterior ankleClinical outcomesOutcome scoresPatient satisfactionT-scoreOutcomes Measurement Information System (PROMIS) pain interferencePain interference T-scoresMean body mass indexExcellent patient-reported outcomesPain intensity domainsWork/sportRetrospective cohort studySignificant pain reductionPostoperative outcome scoresAnkle Outcome ScoreLow complication ratePosterior ankle impingementPatient-reported outcomesSports activitiesHigh patient satisfactionSport-specific activitiesStandard arthroscopic proceduresWilcoxon signed-rank testMean follow
2021
Are Arthroplasty Procedures Really Better in the Treatment of Complex Proximal Humerus Fractures? A Comprehensive Meta-Analysis and Systematic Review.
Pizzo R, Gianakos A, Haring R, Gage M, Stevens N, Liporace F, Yoon R. Are Arthroplasty Procedures Really Better in the Treatment of Complex Proximal Humerus Fractures? A Comprehensive Meta-Analysis and Systematic Review. Journal Of Orthopaedic Trauma 2021, 35: 111-119. PMID: 33079841, DOI: 10.1097/bot.0000000000001926.Peer-Reviewed Original ResearchConceptsComplex proximal humerus fracturesProximal humerus fracturesActive forward flexionHumerus fracturesTotal shoulder arthroplastyInternal fixationForward flexionShoulder arthroplastySystematic reviewOpen reduction internal fixationReverse total shoulder arthroplastyOutcomes of ORIFTherapeutic Level IVReduction internal fixationHigher Constant scoreBetter outcome scoresCochrane Library databasesSimple fracture patternsEnglish-language studiesBasic science studiesComprehensive Meta-AnalysisTotal patientsConstant scoreOpen reductionOutcome scores
2020
Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes?
Gianakos A, Okedele O, Flynn S, Kennedy J, DiGiovanni C. Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes? Foot & Ankle Orthopaedics 2020, 5: 2473011420s00227. PMCID: PMC8696434, DOI: 10.1177/2473011420s00227.Peer-Reviewed Original ResearchAutologous osteochondral transplantationFemale patientsTalar osteochondral lesionsOsteochondral lesionsMale patientsMOCART scoreOsteochondral transplantationKnee donor-site morbidityCartilage repair tissue (MOCART) scoreMean MOCART scoreLonger symptom durationAnkle Outcome ScoreDonor site morbidityMean FAOSSymptom durationFAOS scoresComplication rateConsecutive patientsMagnetic resonance observationOutcome scoresFunctional outcomeMean MRIRevision surgeryPatientsLesion sizeOutcomes Following Arthroscopy for Anterior Impingement in the Ankle Joint: Need for Gender as a Variable in Analysis
Gianakos A, Ivander A, DiGiovanni C, Kennedy J. Outcomes Following Arthroscopy for Anterior Impingement in the Ankle Joint: Need for Gender as a Variable in Analysis. Foot & Ankle Orthopaedics 2020, 5: 2473011420s00229. PMCID: PMC8704851, DOI: 10.1177/2473011420s00229.Peer-Reviewed Original ResearchAnterior ankle impingementComplication rateAnkle impingementFunctional outcomeSystematic reviewAverage complication rateCommon associated pathologyExcellent functional outcomeFunctional outcome scoresMajority of patientsLow complication rateSystematic literature searchAnteromedial impingementMeniscoid lesionsFFI scoresClinical outcomesMale patientsAnterior impingementArthroscopic interventionCochrane DatabaseOutcome scoresArthroscopic treatmentPatient satisfactionArthroscopic evaluationWorse outcomesCartiva Hemiarthroplasty for the Treatment of Hallux Rigidus
Hoskins T, Patel J, Goyette D, Mazzei C, Gianakos A, Koss J, Wittig J, Epstein D. Cartiva Hemiarthroplasty for the Treatment of Hallux Rigidus. Foot & Ankle Orthopaedics 2020, 5: 2473011420s00257. PMCID: PMC8705134, DOI: 10.1177/2473011420s00257.Peer-Reviewed Original ResearchSynthetic cartilage implant hemiarthroplastyFirst metatarsophalangeal jointHallux rigidusSurgical interventionMetatarsophalangeal jointExact testAnkle scoring systemDirect patient examinationSynthetic cartilage implantAmerican Orthopaedic FootCommon surgical interventionFunctional outcome scoresRetrospective chart reviewAdvanced hallux rigidusViable treatment optionFischer's exact testStandard of treatmentProximal phalanx osteotomyDorsal cheilectomyFAOS scoresOrthopaedic FootChart reviewOutcome scoresDegenerative arthritisPatient cohortOutcomes Following Microfracture for Osteochondral Lesions of the Talus in Female Patients
Williamson E, Gianakos A, Hurley E, Kennedy J. Outcomes Following Microfracture for Osteochondral Lesions of the Talus in Female Patients. Foot & Ankle Orthopaedics 2020, 5: 2473011420s00495. PMCID: PMC8696304, DOI: 10.1177/2473011420s00495.Peer-Reviewed Original ResearchMagnetic resonance imagingCartilage repair tissueFemale patientsMOCART scoreOsteochondral lesionsPostoperative FAOS scoresSymptomatic osteochondral lesionsMean patient ageAnkle Outcome ScoreShort Form-12Treatment of OLTSF-12 scoresLong-term outcomesRepair tissueBone marrow stimulationFAOS scoresFurther surgeryMagnetic resonance observationPatient ageClinical outcomesOutcome scoresTerm outcomesDistraction arthroplastyRetrospective analysisPatientsEffect of Microfracture on Functional Outcomes and Subchondral Sclerosis Following Distraction Arthroplasty of the Ankle Joint
Gianakos A, Haring R, Shimozono Y, Fragomen A, Kennedy J. Effect of Microfracture on Functional Outcomes and Subchondral Sclerosis Following Distraction Arthroplasty of the Ankle Joint. Foot & Ankle International 2020, 41: 631-638. PMID: 32354229, DOI: 10.1177/1071100720917144.Peer-Reviewed Original ResearchConceptsPost-traumatic osteoarthritisDistraction arthroplastyAnkle jointOutcomes of patientsAnkle Outcome ScoreFunctional activity levelBone marrow aspirateFAOS scoresOutcome scoresFunctional outcomeAnkle arthrodesisSubchondral sclerosisBiologic augmentationMarrow aspiratesPatientsLevel IIIPoor candidatesDemographic dataJoint replacementEnd stageArthroplastyAdverse effectsRole of microfracturesActivity levelsSame time interval
2018
Microfracture of subchondral bone leads to persistent subchondral sclerosis and poorer functional outcomes following distraction arthroplasty of the ankle joint while biologic augment may improve recovery times
Gianakos A, Kennedy J. Microfracture of subchondral bone leads to persistent subchondral sclerosis and poorer functional outcomes following distraction arthroplasty of the ankle joint while biologic augment may improve recovery times. Foot & Ankle Orthopaedics 2018, 3: 2473011418s00056. DOI: 10.1177/2473011418s00056.Peer-Reviewed Original ResearchAnkle distractionFunctional outcomeLong-term clinical outcomesSubchondral boneTerm clinical outcomesAnkle Outcome ScoreGood functional outcomeRecords of patientsPoor functional outcomeTreatment of ankleSubchondral bone sclerosisJoint spaceChi-square testingJoint space changesMean followPostoperative rangeAnkle osteoarthritisComplication rateArthroplasty resultsBiologic agentsClinical outcomesAnkle arthritisOutcome scoresMean ageBone sclerosis
2015
Anterolateral Tibial Osteotomy for Accessing Osteochondral Lesions of the Talus in Autologous Osteochondral Transplantation
Gianakos A, Hannon C, Ross K, Newman H, Egan C, Deyer T, Kennedy J. Anterolateral Tibial Osteotomy for Accessing Osteochondral Lesions of the Talus in Autologous Osteochondral Transplantation. Foot & Ankle International 2015, 36: 531-538. PMID: 25576475, DOI: 10.1177/1071100714563308.Peer-Reviewed Original ResearchConceptsAutologous osteochondral transplantationAnterolateral tibial osteotomyTibial osteotomyOutcome scoresOsteochondral transplantationOsteochondral lesionsMagnetic resonance imaging outcomesCystic osteochondral lesionsPrimary treatment strategyAnkle Outcome ScoreFunctional outcome scoresRetrospective case seriesRecords of patientsSeries of patientsRepair siteRepair tissueAverage MOCART scoreT2 mapping MRIBone marrow stimulationCartilage repair tissuePostoperative footLigament disruptionLimited morbidityMagnetic resonance observationCase series