2023
Advances in Cartilage Repair
Azam M, Butler J, Duenes M, McAllister T, Walls R, Gianakos A, Kennedy J. Advances in Cartilage Repair. Orthopedic Clinics Of North America 2023, 54: 227-236. PMID: 36894294, DOI: 10.1016/j.ocl.2022.11.007.Peer-Reviewed Original ResearchConceptsAutologous osteochondral transplantationBone marrow stimulationPoor healing capacityAnkle painUncontained lesionsConservative managementArthroscopic debridementCystic lesionsBiological adjuvantsTraumatic etiologyOsteochondral transplantationInvasive proceduresOsteochondral lesionsLarge lesionsMarrow stimulationAnkle jointLesionsSmall lesionsScaffold-based therapiesHealing capacityPatientsArticular cartilageUnsatisfactory resultsCartilage repairDebridement
2018
Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis
Hurley E, Yasui Y, Gianakos A, Seow D, Shimozono Y, Kerkhoffs G, Kennedy J. Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis. Knee Surgery, Sports Traumatology, Arthroscopy 2018, 26: 3499-3507. PMID: 29713784, DOI: 10.1007/s00167-018-4955-x.Peer-Reviewed Original ResearchConceptsStromal vascular fractionPlatelet-rich plasmaTreatment of osteoarthritisClinical outcomesSystematic reviewForm of SVFUse of SVFAdipose-derived stem cell therapyEffects of ADSCsIncidence of swellingFavorable clinical outcomeLevel IV studiesCochrane Library databasesEffects of AdiposeDonor siteStem cell therapySVF injectionComplication rateBiological adjuvantsClinical studiesLevel IVExclusion criteriaLibrary databasesSide effectsAdipose tissue