2015
Proteomic Analysis of the Pericyte Derived Extracellular Matrix
Brown L, Sava P, Garcia C, Gonzalez A. Proteomic Analysis of the Pericyte Derived Extracellular Matrix. Cellular And Molecular Bioengineering 2015, 8: 349-363. DOI: 10.1007/s12195-015-0408-5.Peer-Reviewed Original ResearchMatrix proteinsStructural ECM proteinsBasic cellular responsesExtracellular matrix proteinsFunctional annotationProteomic analysisRegulatory signalsCell rufflingECM proteinsCellular responsesWestern blot analysisECM componentsExtracellular matrixEndothelial cell tubule formationFirst characterizationProteinMigratory velocityBlot analysisTubule formationECMNeutrophil polarizationStructural collagenVascular integrityLC/MS-MSBasement membrane
2014
Chemically- and mechanically-tunable porated polyethylene glycol gels for leukocyte integrin independent and dependent chemotaxis
Lauridsen H, Walker B, Gonzalez A. Chemically- and mechanically-tunable porated polyethylene glycol gels for leukocyte integrin independent and dependent chemotaxis. Technology 2014, 2: 133-143. DOI: 10.1142/s2339547814500113.Peer-Reviewed Original ResearchHuman extracellular matrixExtracellular matrixInflammatory researchECM compositionBiochemical propertiesDependent chemotaxisProtein presentationProtein conjugationLeukocyte integrinsGrowth factorPolyethylene glycol hydrogelsGlass coverslipsGlycol hydrogelsPolyethylene glycol gelComplex mixturesProteinIntegrinsHydrogel pore sizeTranswellProteoglycansChemotaxisChronic inflammatory diseaseRecruitmentMembraneLeukocyte migration
2012
Approaches in extracellular matrix engineering for determination of adhesion molecule mediated single cell function
Ayres-Sander C, Gonzalez A. Approaches in extracellular matrix engineering for determination of adhesion molecule mediated single cell function. Frontiers In Biology 2012, 8: 32-49. DOI: 10.1007/s11515-012-1199-x.Peer-Reviewed Original ResearchCell-ECM interactionsCell adhesion moleculeExtracellular matrixThree-dimensional matrixCellular processesNative extracellular matrixAdhesion moleculesTwo-dimensional substratesSingle cell functionCell functionCell movementECM proteinsNative proteinPeptide sequencesIntegrin expressionBioactive peptide sequencesCell functionalityMatrix engineeringProteinHuman tissuesCellsDiseased tissuesCadherinMoleculesTissue