Deep phenotyping towards precision psychiatry of first-episode depression — the Brain Drugs-Depression cohort
Jensen K, Dam V, Ganz M, Fisher P, Ip C, Sankar A, Marstrand-Joergensen M, Ozenne B, Osler M, Penninx B, Pinborg L, Frokjaer V, Knudsen G, Jørgensen M. Deep phenotyping towards precision psychiatry of first-episode depression — the Brain Drugs-Depression cohort. BMC Psychiatry 2023, 23: 151. PMID: 36894940, PMCID: PMC9999625, DOI: 10.1186/s12888-023-04618-x.Peer-Reviewed Original ResearchConceptsQuick Inventory of Depressive SymptomatologyFirst-episode depressionTreatment packageFirst-episode MDD patientsInventory of Depressive SymptomatologyBackgroundMajor depressive disorderSecond-line antidepressantsHeterogeneous brain disordersMarkers of treatment responseMedication side effectsMDD patientsDepressive disorderDepression severityDepressive symptomatologyPrecision psychiatrySymptom ChecklistClinical outcomesNeuroimaging dataBrain positron emission tomographyPublic outpatient clinicsDisability ScalePositron emission tomographyBrain disordersEffect of treatment choiceDepression