Thread-based assay for quantitative small molecule analysis of mice tear fluid by capillary electrophoresis
Barmada A, Shippy S. Thread-based assay for quantitative small molecule analysis of mice tear fluid by capillary electrophoresis. Analytical And Bioanalytical Chemistry 2018, 411: 329-338. PMID: 30460389, DOI: 10.1007/s00216-018-1488-6.Peer-Reviewed Original ResearchMeSH KeywordsAminesAmino AcidsAnimalsElectrophoresis, CapillaryFemaleFluorescenceMaleMiceSpecimen HandlingTearsConceptsSmall molecule analysisSmall moleculesMolecule analysisMouse tearsChemical compositionCapillary electrophoresis separationMinimal sample handlingHigh separation resolutionSmall volume analysisTear fluidLight-emitting diode-induced fluorescence detectionSeparation resolutionHuman tearsCapillary electrophoresisElectrophoresis separationDiode-induced fluorescence detectionOcular surface diseaseCD-1 malesMicromolar rangePhenol red threadFluorescence detectionSample handlingMoleculesLevels of arginineNon-invasive assay