2020
Quantifying Sample Collection and Processing Impacts on Fiber-Based Tear Fluid Chemical Analysis
Barmada A, Shippy S. Quantifying Sample Collection and Processing Impacts on Fiber-Based Tear Fluid Chemical Analysis. Translational Vision Science & Technology 2020, 9: 23-23. PMID: 33024616, PMCID: PMC7521181, DOI: 10.1167/tvst.9.10.23.Peer-Reviewed Original ResearchConceptsSmall molecule standardsChemical analysisPrimary amine contentLarge volume samplesLight-emitting diode-induced fluorescence detectionPrimary aminesSeparation resolutionCapillary electrophoresisAnalytical techniquesDiode-induced fluorescence detectionTear analysisTear fluid collection
2018
Thread-based assay for quantitative small molecule analysis of mice tear fluid by capillary electrophoresis
Barmada A, Shippy S. Thread-based assay for quantitative small molecule analysis of mice tear fluid by capillary electrophoresis. Analytical And Bioanalytical Chemistry 2018, 411: 329-338. PMID: 30460389, DOI: 10.1007/s00216-018-1488-6.Peer-Reviewed Original ResearchConceptsSmall molecule analysisSmall moleculesMolecule analysisMouse tearsChemical compositionCapillary electrophoresis separationMinimal sample handlingHigh separation resolutionSmall volume analysisTear fluidLight-emitting diode-induced fluorescence detectionSeparation resolutionHuman tearsCapillary electrophoresisElectrophoresis separationDiode-induced fluorescence detectionOcular surface diseaseCD-1 malesMicromolar rangePhenol red threadFluorescence detectionSample handlingMoleculesLevels of arginineNon-invasive assay