2018
Translocation of a gut pathobiont drives autoimmunity in mice and humans
Vieira S, Hiltensperger M, Kumar V, Zegarra-Ruiz D, Dehner C, Khan N, Costa FRC, Tiniakou E, Greiling T, Ruff W, Barbieri A, Kriegel C, Mehta SS, Knight JR, Jain D, Goodman AL, Kriegel MA. Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science 2018, 359: 1156-1161. PMID: 29590047, PMCID: PMC5959731, DOI: 10.1126/science.aar7201.Peer-Reviewed Original ResearchConceptsGut pathobiontAutoimmune-prone miceMurine findingsIntramuscular vaccinePathogenic autoantibodiesLiver biopsyAutoimmune responseAutoimmune patientsAntibiotic treatmentT cellsImmune diseasesAutoimmunitySusceptible humansPathobiontsSystemic tissuesHuman hepatocytesAutoantibodiesMortalityMiceCocultureHepatocytesGenetic backgroundTissueBiopsyPatients
2016
Evaluating Intestinal Infections
Barbieri A, West AB. Evaluating Intestinal Infections. Advances In Anatomic Pathology 2016, 23: 135-143. PMID: 27058242, DOI: 10.1097/pap.0000000000000111.Peer-Reviewed Original ResearchConceptsDifferential diagnosisEvidence of infectionEndoscopic biopsyIntestinal infectionsMucosal infectionsIntestinal mucosaHost reactionSmall intestineInfectious entitiesHistologic sectionsMorphologic compartmentsMucosaInfectionDiagnosisPathologistsPresent studyAutoimmuneCompartmentsBiopsyIntestine