2008
Oscillatory Phosphorylation of Yeast Fus3 MAP Kinase Controls Periodic Gene Expression and Morphogenesis
Hilioti Z, Sabbagh W, Paliwal S, Bergmann A, Goncalves M, Bardwell L, Levchenko A. Oscillatory Phosphorylation of Yeast Fus3 MAP Kinase Controls Periodic Gene Expression and Morphogenesis. Current Biology 2008, 18: 1897. DOI: 10.1016/j.cub.2008.11.024.Peer-Reviewed Original Research
2006
Micro Fluidic Chemostat with Deformable Membranes: Intracellular Biofilm-Like Structure Model
Cho H, Groisman A, Campbell J, Flores S, Levchenko A. Micro Fluidic Chemostat with Deformable Membranes: Intracellular Biofilm-Like Structure Model. 2006, 96-96. DOI: 10.1109/bmn.2006.330906.Peer-Reviewed Original ResearchHost cell membraneMicrofluidic chemostatBacterial cell-cell communicationCell-cell communicationCell membraneIndividual cell behaviorsGene expressionStress responseProtein techniquesHigh-density coloniesBiological stressCell behaviorEscherichia coliBiofilm formationBacterial biofilmsHost organsIntriguing questionChemostatBacterial studiesPathogenic microbiologyMembraneBiofilmsExperimental toolCellsExact mechanismMicrofluidic Chemostat with Deformable Membranes: Intracellular Biofilm-Like Structure Model
Cho H, Groisman A, Campbell J, Flores S, Levchenko A. Microfluidic Chemostat with Deformable Membranes: Intracellular Biofilm-Like Structure Model. 2006, 14-14. DOI: 10.1109/bmn.2006.330900.Peer-Reviewed Original ResearchMicrofluidic chemostatHost cell membraneBacterial cell-cell communicationCell-cell communicationCell membraneIndividual cell behaviorsGene expressionStress responseProtein techniquesHigh-density coloniesBiological stressCell behaviorEscherichia coliBiofilm formationBacterial biofilmsHost organsIntriguing questionChemostatBacterial studiesPathogenic microbiologyMembraneBiofilmsExperimental toolCellsExact mechanism
2002
The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation
Hoffmann A, Levchenko A, Scott M, Baltimore D. The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation. Science 2002, 298: 1241-1245. PMID: 12424381, DOI: 10.1126/science.1071914.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineCell NucleusChemokine CCL5Chemokine CXCL10Chemokines, CXCComputer SimulationCytoplasmDNA-Binding ProteinsElectrophoretic Mobility Shift AssayFeedback, PhysiologicalGene Expression RegulationHumansI-kappa B ProteinsMiceMice, KnockoutModels, BiologicalNF-kappa BNF-KappaB Inhibitor alphaProto-Oncogene ProteinsSignal TransductionTranscriptional ActivationTumor Cells, CulturedTumor Necrosis Factor-alphaConceptsTranscriptional activator NF-kappaBSelective gene activationKnockout cell linesTemporal controlNF-kappaB inhibitor proteinNF-kappaB responseSignaling modulesCoordinated degradationGene activationMammalian cellsNuclear localizationInhibitor proteinGene expressionIkappaB proteinsSignal-processing characteristicsEpsilon functionNF-kappaB activationCell linesNF-kappaB