2017
Associations between self‐reported sleep quality and white matter in community‐dwelling older adults: A prospective cohort study
Sexton C, Zsoldos E, Filippini N, Griffanti L, Winkler A, Mahmood A, Allan C, Topiwala A, Kyle S, Spiegelhalder K, Singh‐Manoux A, Kivimaki M, Mackay C, Johansen‐Berg H, Ebmeier K. Associations between self‐reported sleep quality and white matter in community‐dwelling older adults: A prospective cohort study. Human Brain Mapping 2017, 38: 5465-5473. PMID: 28745016, PMCID: PMC5655937, DOI: 10.1002/hbm.23739.Peer-Reviewed Original ResearchConceptsWhite matter microstructurePoor sleep qualitySleep qualityPoor sleep quality groupSelf-reported sleep qualitySmall effect sizesCommunity-dwelling membersHum Brain MappDiffusion tensorRadial diffusivity valuesVoxel-wise analysisWhite matter measuresCurrent sleep qualityEffect sizeGlobal fractional anisotropyModifiable factorsLifestyle measuresSleep disturbancesPoor sleepSub studyGeneral cognitive functionNeurological illnessAxial diffusivityCognitive functionFractional anisotropy
2010
Genetic control over the resting brain
Glahn DC, Winkler AM, Kochunov P, Almasy L, Duggirala R, Carless MA, Curran JC, Olvera RL, Laird AR, Smith SM, Beckmann CF, Fox PT, Blangero J. Genetic control over the resting brain. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 1223-1228. PMID: 20133824, PMCID: PMC2824276, DOI: 10.1073/pnas.0909969107.Peer-Reviewed Original ResearchConceptsDefault-mode functional connectivityDefault mode connectivityFunctional connectivityDefault mode networkGenetic factorsPosterior cingulate/precuneus regionBasal neural activityResting-state brain networksGray matter densityMedial prefrontal cortexLeft parahippocampal regionIntrinsic brain functionPsychiatric illnessNeurological illnessNeurophysiologic mechanismsAnatomic variationsRight cerebellumSuch illnessesParahippocampal regionBrain functionPrecuneus regionsPrefrontal cortexIllnessGenetic riskNeural activity