Microbial nitrogen limitation in the mammalian large intestine
Reese A, Pereira F, Schintlmeister A, Berry D, Wagner M, Hale L, Wu A, Jiang S, Durand H, Zhou X, Premont R, Diehl A, O’Connell T, Alberts S, Kartzinel T, Pringle R, Dunn R, Wright J, David L. Microbial nitrogen limitation in the mammalian large intestine. Nature Microbiology 2018, 3: 1441-1450. PMID: 30374168, PMCID: PMC6264799, DOI: 10.1038/s41564-018-0267-7.Peer-Reviewed Original ResearchConceptsNitrogen limitationMicrobial nitrogen limitationHost-microbe interactionsGut microbial ecosystemMicrobial symbiontsHost useEcological communitiesMicrobial communitiesMammal speciesCommensal taxaPhylum BacteroidetesNitrogen availabilityDietary nutrientsMammalian large intestineResource limitationsNitrogen supplyTotal nitrogen supplyProtein levelsResource supplyCommensal microbiotaMicrobiomeLarge intestineGerm-free miceExcess dietary proteinHost