Catecholamine influences on prefrontal cortex circuits and function
Arnsten A, Berridge C. Catecholamine influences on prefrontal cortex circuits and function. 2014, 161-173. DOI: 10.1017/cbo9781139035491.015.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderHyperactivity disorderManagement of ADHDDiagnosis of ADHDChronic neurobehavioral disorderPrefrontal cortex circuitCatecholamine influenceCortex circuitTreatment modalitiesPsychiatric illnessNeurobehavioral disordersClinical optionBipolar disorderSocial workersDisordersRecent researchDiagnosisAdultsChildrenDevelopmental processesDistractibilityImpulsivityPsychologistsComorbiditiesWorld-renowned expertsGuanfacine extended release for the treatment of attention-deficit/hyperactivity disorder in children and adolescents
Connor DF, Arnsten A, Pearson GS, Greco GF. Guanfacine extended release for the treatment of attention-deficit/hyperactivity disorder in children and adolescents. Expert Opinion On Pharmacotherapy 2014, 15: 1601-1610. PMID: 24992513, DOI: 10.1517/14656566.2014.930437.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderHyperactivity disorderSymptoms of ADHDEvidence-based treatmentsTraumatic stressBehavioral dysregulationADHD studiesSmall effect sizesPrefrontal cortexAdolescents 6Behavioral conditionsAdolescentsEffect sizeGXRPsycINFO databasesGuanfacinePsychostimulantsShire PharmaceuticalsOpen trialChildrenPotential promiseSecond-line treatmentDisordersAntihypertensive agentsAdrenoreceptor agonist