2023
Neurosteroid pathway derangement in asphyctic infants treated with hypothermia: an untargeted metabolomic approach
Valerio E, Stocchero M, Pirillo P, D’Errico I, Bonadies L, Galderisi A, Giordano G, Baraldi E. Neurosteroid pathway derangement in asphyctic infants treated with hypothermia: an untargeted metabolomic approach. EBioMedicine 2023, 92: 104636. PMID: 37257315, PMCID: PMC10244906, DOI: 10.1016/j.ebiom.2023.104636.Peer-Reviewed Original ResearchConceptsAsphyctic infantsHypoxic-ischemic encephalopathyHealthy newbornsPerinatal asphyxiaMetabolic effectsSingle-center longitudinal studyDays of lifeTherapeutic hypothermiaUrinary metabolomePathobiological mechanismsSteroid levelsInfantsHypothermiaSteroidogenesis pathwayUntargeted metabolomics approachNewbornsSteroid contentTranslational researchLongitudinal studyPotential roleAsphyxiaEncephalopathyMetabolomics approachPathway analysisUntargeted metabolomicsClinical features of neonatal COVID-19
Galderisi A, Lista G, Cavigioli F, Trevisanuto D. Clinical features of neonatal COVID-19. Seminars In Fetal And Neonatal Medicine 2023, 28: 101430. PMID: 37005209, PMCID: PMC10036147, DOI: 10.1016/j.siny.2023.101430.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSARS-CoV-2 infectionClinical featuresNeonatal COVID-19Infected mothersHealthy newbornsPsychological health problemsEfforts of cliniciansEpidemiological dataHealth problemsAge groupsInfectionFirst dayHealthcare systemCOVID-19COVID-19 pandemicNewbornsDifferential effectsEntire populationAdditional burdenComorbiditiesPandemicComplicationsNeonatesCliniciansMassive research effort
2022
Glucose-to-lactate ratio and neurodevelopment in infants with hypoxic-ischemic encephalopathy: an observational study
Galderisi A, Tordin M, Suppiej A, Cainelli E, Baraldi E, Trevisanuto D. Glucose-to-lactate ratio and neurodevelopment in infants with hypoxic-ischemic encephalopathy: an observational study. European Journal Of Pediatrics 2022, 182: 837-844. PMID: 36484862, PMCID: PMC9899169, DOI: 10.1007/s00431-022-04694-3.Peer-Reviewed Original ResearchMeSH KeywordsGlucoseHumansHyperglycemiaHypoglycemiaHypothermia, InducedHypoxia-Ischemia, BrainInfantInfant, NewbornLactic AcidConceptsHypoxic-ischemic encephalopathyTherapeutic hypothermiaNeurodevelopmental outcomesLactate ratioDay 1Severe hypoxic-ischemic encephalopathyNew risk markerSevere hypoNeonatal hypoglycemiaMetabolic outcomesRisk markersObservational studyMetabolic variablesDay 2InfantsLactate concentrationEncephalopathyLactate kineticsNeurodevelopmentMetabolic fuelsNeonatesStrongest predictorHypothermiaOutcomesGlucoseGlucose variability increases during minimally invasive procedures in very preterm infants
Galderisi A, Res G, Guiducci S, Savio F, Brigadoi S, Forlani L, Mastrandrea B, Moschino L, Lolli E, Priante E, Trevisanuto D, Baraldi E. Glucose variability increases during minimally invasive procedures in very preterm infants. European Journal Of Pediatrics 2022, 182: 89-94. PMID: 36201017, PMCID: PMC9829573, DOI: 10.1007/s00431-022-04641-2.Peer-Reviewed Original ResearchConceptsVery preterm infantsContinuous glucose monitoringPreterm infantsGlucose variabilityNeonatal stressNappy changeInvasive proceduresMedian glucoseGlucose monitoringNon-invasive procedurePrimary outcomeAbsence of changesHeel prickMean glucoseNeonatal proceduresCare proceduresDay 2InfantsParental presenceGlucose variationCGM dataGlucoseSDNeonatesPrick
2021
Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants
Galderisi A, Trevisanuto D, Russo C, Hall R, Bruschettini M. Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants. 2021, 2021: cd013309. PMID: 34931697, PMCID: PMC8690212, DOI: 10.1002/14651858.cd013309.pub3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRisk of hypoglycaemiaUse of CGMContinuous glucose monitoringPreterm infantsIntermittent modalitiesRisk ratioEffects of CGMLong-term neurodevelopmental impairmentGlucose monitoringEfficacy of CGMCare Group (EPOC) criteriaPreterm infants 1Cochrane Effective PracticePrevention of morbidityClinical trials databasesLong-term outcomesConfidence intervalsPreterm infant mortalitySafety of CGMImprecision of estimatesFixed-effects modelAdverse neurodevelopmentGRADE approachNeurodevelopmental outcomesDATA COLLECTIONNoncommunicable diseases of prematurity: Time for a new mindset?
Baraldi E, Galderisi A. Noncommunicable diseases of prematurity: Time for a new mindset? The Journal Of Pediatrics 2021, 237: 319-320. PMID: 34197887, DOI: 10.1016/j.jpeds.2021.06.064.Peer-Reviewed Original ResearchThe aftermath of SARS-CoV-2 in NICU: saving or checking accounts? Projected cost-effectiveness analysis
Galderisi A, Lolli E, Cavicchiolo M, Bonadies L, Trevisanuto D, Baraldi E. The aftermath of SARS-CoV-2 in NICU: saving or checking accounts? Projected cost-effectiveness analysis. European Journal Of Pediatrics 2021, 180: 1631-1635. PMID: 33415468, PMCID: PMC7790311, DOI: 10.1007/s00431-020-03884-1.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitIntensive care unitCare unitNasopharyngeal swabsHospital environmentSARS-CoV-2 pandemicSARS-CoV-2COVID-19 pandemicCOVID-19 testCost-effectiveness analysisNICU personnelScreening programNumber of casesNeonatesHospital managementHigher numberCOVID-19NICUSwabsFuture strategiesPandemicParentsEffective strategyPersonnel
2020
Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants
Galderisi A, Bruschettini M, Russo C, Hall R, Trevisanuto D. Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants. 2020, 12: cd013309. PMID: 33348448, PMCID: PMC8092644, DOI: 10.1002/14651858.cd013309.pub2.Peer-Reviewed Original ResearchConceptsPreterm infantsContinuous glucose monitoringGlycemic measuresRisk ratioIntermittent modalitiesLong-term neurodevelopmental impairmentGlucose monitoringCare Group (EPOC) criteriaCochrane Central RegisterCochrane Effective PracticePrevention of morbidityQuasi-randomized trialStandard search strategyClinical trials databasesLong-term outcomesPreterm infant mortalityAllied Health LiteratureUse of CGMImprecision of estimatesFixed-effects modelCochrane NeonatalAdverse neurodevelopmentCentral RegisterGRADE approachControlled Trials
2019
Neonatal Resuscitation: State of the Art
Trevisanuto D, Galderisi A. Neonatal Resuscitation: State of the Art. American Journal Of Perinatology 2019, 36: s29-s32. PMID: 31238355, DOI: 10.1055/s-0039-1691797.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNeonatal resuscitationSustained lung inflationUmbilical cord milkingInvasive surfactant administrationUmbilical cord clampingManagement of neonatesHeart rate assessmentForthcoming clinical trialsCord clampingSurfactant administrationCord milkingPreterm infantsNew RCTsLaryngeal maskClinical trialsLung inflationRobust scientific evidenceResuscitationLiterature searchRelevant articlesPast yearScientific evidenceDescriptive reviewRCTsNovel evidenceAirway Histopathology of Adolescent Survivors of Bronchopulmonary Dysplasia
Galderisi A, Calabrese F, Fortarezza F, Abman S, Baraldi E. Airway Histopathology of Adolescent Survivors of Bronchopulmonary Dysplasia. The Journal Of Pediatrics 2019, 211: 215-218. PMID: 31076230, DOI: 10.1016/j.jpeds.2019.04.006.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasiaChronic obstructive lung diseaseSevere bronchopulmonary dysplasiaObstructive lung diseaseLong-term survivorsAdolescent survivorsT helper lymphocytesAirway histopathologyAirway processesBronchial biopsiesLymphocytic infiltrateLung diseaseDysplasiaSurvivorsBasement membraneHistopathologyInfiltratesBronchopulmonaryBiopsyEosinophilsLymphocytesNeoangiogenesisDisease
2017
The distance between the delivery room and neonatal intensive care unit had no impact on the respiratory management of preterm infants at birth
Trevisanuto D, Morassutti F, Doglioni N, Avilés C, Galderisi A, Cavallin F. The distance between the delivery room and neonatal intensive care unit had no impact on the respiratory management of preterm infants at birth. Acta Paediatrica 2017, 107: 171-172. PMID: 28981170, DOI: 10.1111/apa.14107.Peer-Reviewed Original Research
2015
i-gel: a new supraglottic device for effective resuscitation of a very low birthweight infant with Cornelia de Lange syndrome
Galderisi A, De Bernardo G, Lorenzon E, Trevisanuto D. i-gel: a new supraglottic device for effective resuscitation of a very low birthweight infant with Cornelia de Lange syndrome. BMJ Case Reports 2015, 2015: bcr2014209124. PMID: 25809435, PMCID: PMC4386302, DOI: 10.1136/bcr-2014-209124.Peer-Reviewed Case Reports and Technical NotesConceptsLaryngeal mask airwayLow birthweight infantsBirthweight infantsCornelia de Lange syndromeNew supraglottic airway deviceClassic laryngeal mask airwayDe Lange syndromeNew supraglottic deviceFace mask ventilationSupraglottic airway deviceWeeks of gestationLange syndromeMask airwaySupraglottic devicesAirway devicesAirway managementEffective resuscitationI-gelInfantsEffective ventilationTrainee paediatriciansCurrent reportFirst caseSyndromeVentilation
2014
An easy, fast, effective tool to monitor the incidence of type 1 diabetes among children aged 0–4 years in Italy: the Italian Hospital Discharge Registry (IHDR)
Vichi M, Iafusco D, Galderisi A, Stazi M, Nisticò L. An easy, fast, effective tool to monitor the incidence of type 1 diabetes among children aged 0–4 years in Italy: the Italian Hospital Discharge Registry (IHDR). Acta Diabetologica 2014, 51: 287-294. PMID: 24473635, DOI: 10.1007/s00592-014-0556-4.Peer-Reviewed Original ResearchConceptsType 1 diabetes incidenceType 1 diabetesHospital Discharge RegistryDiabetes incidenceDischarge RegistryFirst hospitalizationFirst hospitalization ratesPublic health purposesIncident hospitalizationHospitalization ratesCalendar periodPrevalent casesFirst episodeHospitalizationDiabetesOverall populationNational ratesIncidenceAge rangeYear residentsHealth purposesNational dataRegistryRecord linkage procedureChildren
2013
Six cases with severe insulin resistance (SIR) associated with mutations of insulin receptor: Is a Bartter-like syndrome a feature of congenital SIR?
Grasso V, Colombo C, Favalli V, Galderisi A, Rabbone I, Gombos S, Bonora E, Massa O, Meschi F, Cerutti F, Iafusco D, Bonfanti R, Monciotti C, Barbetti F. Six cases with severe insulin resistance (SIR) associated with mutations of insulin receptor: Is a Bartter-like syndrome a feature of congenital SIR? Acta Diabetologica 2013, 50: 951-957. PMID: 23824322, DOI: 10.1007/s00592-013-0490-x.Peer-Reviewed Case Reports and Technical NotesConceptsSevere insulin resistanceRabson-Mendenhall syndromeDonohue syndromePatient 3Insulin resistanceAbsence of hypertensionGene mutationsINSR mutationsInsulin receptor gene mutationsBartter-like syndromeBartter syndrome type IIReceptor gene mutationsYear of birthSevere hirsutismClinical featuresFifth patientPotassium supplementationAcanthosis nigricansHyperreninemic hyperaldosteronismRenal abnormalitiesCongenital syndromePatientsPubertal femalesSyndromeINSR gene
2011
All classifications not built on pathogenesis become inadequate sooner or later
Iafusco D, Galderisi A, Lombardo F, Scaramuzza A, Tartaglia E, Cocca A, Giugliano R, Giugliano B, Sena T, Napoli A, Mastrantonio P, Stoppoloni F, Prisco F. All classifications not built on pathogenesis become inadequate sooner or later. Diabetologia 2011, 54: 1583-1584. PMID: 21400041, DOI: 10.1007/s00125-011-2113-9.Commentaries, Editorials and Letters